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Aulia, Muhammad Budi
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Efek Pemberian Zinc Oksida 13 % Topikal Terhadap Penyembuhan Luka Sayat Pada Tikus Putih Galur Wistar (Rattus Norvegicus) Aulia, Muhammad Budi; Andrini, Nita
JURNAL PANDU HUSADA Vol 6, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v6i1.21069

Abstract

Abstrak : Luka adalah suatu kondisi dimana terputusnya kontinuitas struktur anatomi kulit yang bervariasi dimulai dari lapisan epitel dari kulit, sampai lapisan yang lebih dalam seperti jaringan subkutis, lemak dan otot. Penyembuhan luka dipengaruhi oleh beberapa faktor seperti asupan nutrisi, infeksi, status imunologi, dan penyakit-penyakit penyerta. Beberapa nutrisi yang berperan dalam mempercepat penyembuhan luka seperti vitamin C, zinc, dan protein. Tujuan : Penelitian ini bertujuan untuk mengetahui efek pemberian zinc oksida 13 %  topikal terhadap penyembuhan luka sayat pada tikus putih galur wistar. Metode: Penelitian ini berjenis experimental dengan desain penelitian true experiment dengan rancangan  pre-test post-test control group design. Subjek penelitian yang diambil dengan metode purposive sampling diperoleh masing-masing sebanyak 15 ekor pada kelompok perlakuan dan kelompok kontrol. Data analisis menggunakan uji Wilcoxon dan uji Mann Whitney. Hasil: Uji Wilcoxon menunjukkan p=0.001 (p0.05) sehingga terdapat perbedaan antara kondisi luka sebelum dan setelah pemberian zinc oksida 13% topikal pada kelompok perlakuan dan kelompok kontrol. Uji Mann Whitney menunjukkan terdapat pengaruh pemberian zinc oksida 13% topikal terhadap proses penyembuhan luka sayat pada tikus putih galur wistar (p=0.000). Kesimpulan: Pemberian zinc oksida 13% topikal berpengaruh terhadap penyembuhan luka sayat pada tikus galur wistar.
Comorbid Diabetes Mellitus and Hypertension Are Associated with Istithaah Status in Hajj Pilgrims Boy, Elman; Khoiriyah, Nadia; Aulia, Muhammad Budi; Ginting, Azzura Sufina; Saragih, Muhammad Raka Zaelani; Khairunisa, Sukma
Biomedika Vol 17, No 1 (2025): Biomedika Februari 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i1.6509

Abstract

Hajj pilgrim health istithaah is empowering the congregation's health through quantifiable physical and mental assessments so that the congregation can carry out their worship by Islamic religious guidance. Indonesian Hajj pilgrims are generally elderly and have a high risk of health problems. Common health problems like hypertension and diabetes mellitus. This study objective to analyze the impact of comorbid diabetes mellitus and hypertension on the health status of Hajj pilgrims. Cross-sectional observational analysis was employed in this study. The subjects used simple random sampling and the number of respondents was 289. Data analysis used statistical analysis tests using SPSS. Univariate and bivariate analyses are used in the data analysis. The results of the bivariate analysis between comorbid diabetes mellitus and istithaah status using Chi-Square test showed that p=0.04 (p<0.05) and Spearman Correlation test showed that p=0.01 (p<0.05). The results of the bivariate analysis between comorbid hypertension and istithaah status using Chi-Square test showed that p=0.01 (p<0.05) and Spearman Correlation test showed that p=0.01 (p<0.05). There is a significant relationship between comorbidities of diabetes mellitus and hypertension with istithaah status among prospective Hajj pilgrims embarking in Medan City, North Sumatra Province in 2024
Co-Authors ELMAN BOY Ginting, Azzura Sufina Khairunisa, Sukma Khoiriyah, Nadia Nita Andrini Saragih, Muhammad Raka Zaelani