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All Journal Jurnal Ners Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Dedi Sutia
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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HUBUNGAN TEKANAN DARAH SISTOLIK DENGAN OUTCOME STROKE PADA PASIEN DENGAN DAN TANPA INTRACRANIAL LARGE ARTERY STENOSIS Dedi Sutia; Syarif Indra; Andi Fadilah Yusran Putri; Firstisa Nuzulia K
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i1.311

Abstract

Blood pressure in acute onset of ischemic stroke usually increase in patients with intracranial artery stenosis. The aim of increasing blood pressure in this situation is to maintain cerebral autoregulation, meanwhile increased blood pressure in acute onset of ischemic stroke is associated with poor clinical outcomes. This study aims to determine the association between systolic blood pressure and stroke outcomes in patients with and without intracranial large artery stenosis which will help the clinician to determine the prognosis in acute ischemic stroke patients. This study used a cross-sectional design. The population of this study was ischemic stroke patients with or without intracranial arterial stenosis based on the results of transcranial doppler ultrasonography in the neurology department of RSUP Dr. M. Djamil Padang from January 2018 - July 2018. P-value <0.05 was considered statistically significant. In 25 subjects, there were 9 males (36%) and 16 females (64%) based on the gender category.There was a significant difference in systolic blood pressure in both groups (p=0.035). There was no significant difference in MRS values in both groups (p=0.480). There was no significant difference between systolic blood pressure and MRS values in patients with intracranial large artery stenosis (p=0.579) and patients without intracranial large artery stenosis (p=0.481). There was no association between systolic blood pressure and stroke outcome in patients with and without intracranial large artery stenosis.
Hubungan Kadar Apolipoprotein B dengan Tingkat Keparahan Stroke Iskemik Jabbar, Ridho Ahmad; Indra, Syarif; Dedi Sutia; Syafrita, Yuliarni; Susanti, Restu; Putri, Fanny Adhy
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.49865

Abstract

Background: Stroke is a leading cause of disability and the second leading cause of death worldwide. Ischemic stroke occurs due to vascular occlusion that restricts blood supply to the brain. Apolipoprotein B (ApoB) is the main component of atherogenic lipoprotein particles, which plays a role in the pathogenesis of atherosclerosis. The NIHSS is recommended as a valid and accessible tool for assessing the severity of acute stroke. Although ApoB has been studied as a lipid biomarker, evidence regarding its association with the severity of ischemic stroke remains limited. Methods: This cross-sectional study included 72 ischemic stroke patients with onset <72 hours who were admitted to Dr. M. Djamil General Hospital, Padang, from February 2025 to July 2025. Data were collected through interviews, physical examinations, supporting investigations, and laboratory tests. ApoB levels were measured using the ELISA method, and stroke severity was assessed using the NIHSS. Data analysis was performed using SPSS version 30.0, with statistical significance set at p < 0.05. Results: The mean Apolipoprotein B level was 105.25 mg/dL. Based on NIHSS assessment, patients with moderate stroke severity accounted for 43.1%, followed by mild stroke (37.5%) and severe stroke (19.4%). Statistical analysis showed no significant association between Apolipoprotein B levels and ischemic stroke severity (p = 0.614). Conclusion: There was no association between Apolipoprotein B levels and ischemic stroke severity.
Co-Authors Andi Fadilah Yusran Putri Firstisa Nuzulia K Indra, Syarif Jabbar, Ridho Ahmad Putri, Fanny Adhy Restu Susanti Syarif Indra Yuliarni Syafrita