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Hubungan Masa Kerja Dengan Kejadian Dermatitis Kontak Akibat Kerja Pada Cleaning Service Di Rumah Sakit Umum Cut Meutia Aceh Utara Erida, Bela Nurfitri; Sawitri, Harvina; Mellaratna, Wizar Putri
Lentera : Jurnal Ilmiah Sains, Teknologi, Ekonomi, Sosial, dan Budaya Vol. 8 No. 4: LENTERA, DESEMBER 2024
Publisher : LPPM Universitas Almuslim

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Abstract

Occupational contact dermatitis is a skin condition caused by exposure to materials used at work. Cleaning service is a person who is in charge of maintaining cleanliness and providing cleaning services that have the potential to experience occupational contact dermatitis. The purpose of this study was to the relationship between years of service with the incidence of occupational contact dermatitis in the cleaning service workers at the cut meutia general hospital, north aceh. The research method used is observational analytic through a cross sectional approach. Sampling in this study used a consecutive sampling technique of 84 people who met the inclusion and exclusion criteria. The measuring instrument used is the NOSQ 2002-LONG questionnaire and the diagnosis is confirmed by the mathias criteria. Analysis of the data from this study used a statistical test in the form of a chi-square test. The results of this study found that most of the respondents were women and adults. Most of the cleaning services at the Cut Meutia Aceh Utara General Hospital have a working period of >2 years (79.8%). Cleaning service at the Cut Meutia General Hospital, North Aceh who experienced contact dermatitis due to work as many as 45 people (53.6%). The conclusion is that there is no significant relationship between years of service with the incidence of occupational contact dermatitis in the cleaning service workers at the cut meutia general hospital, north aceh. with a p value of 0.448 (p > 0.05).
Aripiprazole Erida, Bela Nurfitri; Octiva, Suzanna
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol. 4 No. 1 (2025): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - Februari 2
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v4i1.19260

Abstract

Aripiprazole adalah obat antipsikotik generasi kedua yang biasa digunakan untuk mengobati skizofrenia. Aripiprazole dikenal sebagai "penstabil sistem dopamin" dengan mekanisme aksi yang memberikan agonisme parsial dengan afinitas tinggi pada dopamin D2 dan serotonin-5-HT1A reseptor serta antagonisme pada serotonin-5-HT2A reseptor dan menunjukkan bukti kemanjuran klinis yang baik dengan profil keamanan dan tolerabilitas yang menguntungkan pada pasien dengan skizofrenia. Mekanisme kerja dari aripiprazole dianggap memungkinkan obat tersebut untuk memblokir jalur akibat kelebihan dopamin yang dapat menyebabkan psikosis, sementara pada saat yang sama aripiprazole dapat merangsang daerah otak untuk melakukan pengurangan terhadap dopamin sehingga dapat mengurangi efek samping. Karena insiden efek samping yang lebih rendah, aripiprazole sering dipilih sebagai pengobatan lini pertama untuk episode pertama psikosis.