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Pengaruh Jalan Kaki Terhadap Kadar Gula Darah Sewaktu pada Penderita Diabetes Melitus Tipe 2 di Kelurahan Tuminting Kota Manado Rizkan Halalan Djafar; Christiva Maras; Sarwan Sarwan; Cut Mutya Bunsal; Agust A Laya
Jurnal Kesehatan Amanah Vol. 8 No. 2 (2024): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v8i2.671

Abstract

Sugar levels that accumulate in the blood due to not being absorbed well by body cells can cause various organ disorders. If not controlled properly, it can lead to various complications that can be life-threatening. Risk factors that can affect blood sugar levels are food, activity, and weight gain. Therefore, one way to keep blood sugar levels under control is by doing walking therapy activities. The purpose of this study was to determine the effect of walking on the fasting blood sugar levels when in patients with type 2 diabetes mellitus in Tuminting Village, Manado City. This research is a quantitative research with a method used pre-experimental method using a with a pre-test-post test one group design approach. The sample was taken based on the number of respondents obtained as many as 19 people using Purposive sampling. Data collection was done by using blood glucose test tools and observation sheets. The results of data analysis using the Paired sample t-test showed P value of 0.001 or smaller than ≤0.05 which means that the alternative hypothesis Ha is accepted or through walking activities can reduce the fasting blood sugar levels when in patients with type 2 diabetes mellitus. The conclusion is that the waking activities can reduce blood sugar levels in patients with type 2 diabetes mellitus in Tuminting Village, Manado City. It is suggested to people with diabetes mellitus to be able to apply this walking therapy to help control their blood sugar levels.
Skrining Fitokimia dan Uji Antioksidan Fraksi Etil Asetat Dari Ekstrak Etanol Daun Kunyit (Curcuma longa L.) Dengan Metode DPPH Julia Megawati Djamal; Hana Rindi Sahea; Agust A Laya
An-Najat Vol. 3 No. 3 (2025): Agustus : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i3.3131

Abstract

Turmeric leaves (Curcuma longa L.) is a traditional medicinal plant that contains secondary metabolites such as flavonoids, tannins, and alkaloids, which have potential as natural antioxidants. This study aims to identify the secondary metabolite content and evaluate the antioxidant activity of the ethyl acetate fraction of the ethanol extract of turmeric leaves using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Extraction was carried out using the maceration method with 96% ethanol as the solvent, followed by liquid-liquid fractionation using ethyl acetate. Qualitative phytochemical screening was performed to detect the presence of bioactive compounds such as alkaloids, flavonoids, tannins, saponins, and steroids, while antioxidant activity was assessed by observing the color change of the DPPH solution. The results showed that the ethyl acetate fraction contained these secondary metabolites and exhibited antioxidant activity, as indicated by a color change from purple to yellow. In conclusion, the ethyl acetate fraction of the ethanol extract of turmeric leaves contains bioactive compounds and has potential as a natural antioxidant source.