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KADAR ANTIBODI IgG SARS COV-2 SETELAH VAKSINASI COVID-19 DOSIS LANJUTAN Fajrunni'mah, Rizana; Purwanti , Angki; Setiawan, Budi
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 2 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i2.1865

Abstract

COVID-19 is a problem throughout the world, including Indonesia. One of the efforts to overcome the COVID-19 pandemic is vaccination. A follow-up or booster dose was needed to increase individual protection because there was a decrease in antibodies 6 months after receiving vaccination. This study aimed to determine SARS-CoV-2 IgG antibody levels before and after 8 months of the third booster vaccination. This research method was observational with a longitudinal, cohort approach to 27 samples using a consecutive sampling technique at the Health Polytechnic of the Ministry of Health, Jakarta III in April-November 2022. The data collection techniques used questionnaires and venous blood sampling to examine quantitative Anti-SARS CoV-2 Ig G levels using the CMIA (Chemiluminescent microparticle immunoassay) method with the Architect tool which was carried out twice, namely before administration and 8 months after the third booster vaccination with a heterologous vaccine. Data were analyzed using a statistical test of the difference between the means of two groups. Based on the research results, although statistically there was no significant difference between before and 8 months after vaccination (p=0.055), there was a decrease in the mean quantitative Anti-SARS CoV-2 IgG level of 5301.24 AU/mL. As many as 63% of subjects experienced a decrease in antibody levels 8 months after vaccination compared to before the third booster vaccination. Longitudinal studies are needed to determine protective antibody levels.
Pengaruh Minum Air Putih terhadap Hasil Pemeriksaan Mikroskopis (Sedimen) Urin Prasetyorini, Tri; Purwanti , Angki; Djayaningrat, Husyain; Putri, Tasha Dwisarah
Jurnal Kesehatan Cendikia Jenius Vol. 1 No. 2 (2024): April
Publisher : CV. CENDIKIA JENIUS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70920/jenius.v1i2.41

Abstract

Chronic Kidney Disease (CKD) is a kidney disorder characterized by abnormalities in kidney structure or function. Based on research results, cases of kidney failure experienced by adults are caused by kidney stones and urinary tract infections which can be caused by foods containing purine, drinking water containing hard water, frequent holding in urination and lack of fluids in the body which can result in dehydration. The aim of this study was to determine whether or not there was an effect of drinking water on urine sediment examination. This research was conducted at the Matraman Community Health Center, the research design in this study was Pre-Experimental, namely a study by carrying out experimental activities to determine the effect of drinking water on the results of microscopic examination (sediment) of urine by providing 2 liters of water or minerals/day once. administered before and after drinking water. This study used the Federer formula with 35 respondents and the results showed no significant differences between urine sediment examination before and after administering 2 liters of water, except for calcium oxalate crystals and uric acid. In conclusion, drinking 2 liters of water for one day has no effect on the results of microscopic examination (sediment) of urine and there are no significant differences between urine sediment examination before and after giving 2 liters of water/day, except for calcium oxalate and uric acid crystals in urine. It is recommended that further research follow up on any factors (influences) that can influence the microscopic examination (sediment) of urine.