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All Journal Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Astika, Rahmila Yuni
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Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KAYU MANIS (Cinnamomum burmanni) PADA MENCIT PUTIH JANTAN Astika, Rahmila Yuni; Sani K, Fathnur; Elisma
Jurnal Ilmiah Manuntung Vol 8 No 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.465

Abstract

Cinnamon (Cinnamomum burmannii) leaves extract contains secondary metabolites such as flavonoids, saponins, tannins, alakloids, steroids/terpenoids and phenols. The aims of this study was to examine the anti-inflammatory activity of the ethanolic extract of cinnamon leaves topically and to determine the best concentration for the treatment of inflammation. This research is an experimental research with a post test only control group design approach. The treatment group was devided into 5 groups where each treatment consisted of 7 test animals The treatments included positive control (hydrocortisone acetate 2.5%), negative control (vaselin flavum), ethanol extract of cinnamon leaves with concentrations of 5%, 10% and 20%. The results showed that the ethanolic extract of cinnamon leaves had an anti-inflammatory effect statistically had a significant difference between the treatment groups (p<0.05). The best concentration is 20% then followed by 10% and 5%.
Co-Authors Elisma Sani K, Fathnur