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Nilsya Febrika Zebua
Program Studi Farmasi, Fakultas Farmasi, Universitas Tjut Nyak Dhien, Medan, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF LEAVES OF MEDICINAL PLANT Hibiscus tiliaceus L. Nilsya Febrika Zebua; Nerdy Nerdy; Refi Bahrianur; Shadiq Suwailim; Said Haikal Alfajar
FORTE JOURNAL Vol 4 No 2 (2024): Edisi Juli 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v4i2.902

Abstract

Antimicrobial agents are very important in the medical world. The agent is used as a surgical and intensive care procedure. However, bacteria have become resistant to the antibiotics used. Apart from that, antioxidants are also needed in the medical world as neuroprotectives and preventing free radicals in the body so as to avoid degenerative diseases. Hibiscus tiliaceus L or better known in Indonesia is a waru plant, containing various active compounds such as alkaloids, flavonoids, tannins and saponins that can be used as alternatives as natural antimicrobials and antioxidants. The purpose of writing this review article is to determine the antimicrobial and antioxidant potential of hibiscus plants (Hibiscus tiliaceus L.). The method used in this review article is a literature study obtained from sciencedirect, researchgate and google scholar regarding the benefits of Hibiscus tiliaceus L. leaf extract as an antimicrobial and antioxidant through a literature search process using research articles from the last 10 years. Based on research that has been carried out, it shows that Hibiscus tiliaceus L. leaves extract has the potential to be a natural antimicrobial and antioxidant.
UJI AKTIVITAS SEDIAAN GEL HAND SANITIZER DARI ASAP CAIR TEMPURUNG KELAPA (Cocos nucifera L.) TERHADAP BAKTERI Staphylococcus aureus Nilsya Febrika Zebua; Sumardi Sumardi; Tari Putri Utami Rizki
FORTE JOURNAL Vol 4 No 2 (2024): Edisi Juli 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v4i2.916

Abstract

Asap cair berperan sebagai antimikroba dan antioksidan, hal ini berkaitan dengan konsentrasi senyawa yaitu fenol, karbonil dan asam. Bakteri Staphylococcus aureus diklasifikasikan sebagai bakteri gram positif dan bakteri yang umum ditemukan pada kulit, saluran hidung, dan saluran pernapasan. Hand sanitizer adalah antiseptik berbentuk gel yang sering digunakan untuk mencuci tangan tanpa air. Salah satu polimer alami yang digunakan adalah galaktomanan. Oleh karena itu, tujuan penelitian ini melakukan formulasi hand sanitizer dengan bahan aktif asap cair tempurung kelapa yang bisa membunuh bakteri Staphylococcus aureus. Penelitian berupa eksperimental dengan tahapan kerja meliputi: pengumpulan asap cair tempurung kelapa, pembuatan galaktomanan dari kolang-kaling, penentuan konsentrasi, uji organoleptik, uji homogenitas, uji pH, uji daya sebar, uji stabilitas sediaan, dan pengujian aktivitas antibakteri sediaan uji iritasi pada sukarelawan. Hasil kesimpulan asap cair tempurung kelapa dapat menghambat pertumbuhan bakteri Staphylococcus aureus paling besar terdapat pada konsentrasi 1,5% yaitu sebesar 12,1 mm dan sediaan gel hand sanitizer asap cair tempurung kelapa memenuhi uji evaluasi. Kemudian kombinasi basis antara galaktomanan dan carbopol 940 dapat dijadikan sebagai basis gel hand sanitizer karna dapat membuat gel hand sanitizer menjadi kental.
REVIEW ARTICLE BENEFIT OF VOLATILE ORGANIC COMPOUNDS IN CITRUS SPECIES Nerdy Nerdy; Nilsya Febrika Zebua; Syarifah Nadia; Kharina Tambunan; Fatia Zahra; Tedy Kurniawan Bakri
FORTE JOURNAL Vol 5 No 1 (2025): Edisi Januari 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v5i1.1092

Abstract

The volatile organic compounds in Citrus species, such as oranges, limes, and lemons, are crucial for both plant ecology and various human applications. This review article explores the diverse benefits of Citrus volatile organic compounds, highlighting their roles in plant defense mechanisms, pollinator attraction, and intraspecies communication. The chemical composition of Citrus volatile organic compounds includes key compounds like limonene, β-linalool, trans-citral, β-myrcene, α-Pinene, β-Pinene, γ-Terpinene, and Terpineol, which exhibit significant anti-microbial, anti-inflammatory, anti-oxidant, and potential anti-cancer properties. These compounds are integral to human health, utilized in aromatherapy, and enhancing mood and reducing anxiety. Industrially, Citrus volatile organic compounds are indispensable in the food and beverage industry as flavoring agents, in cosmetics and personal care products for their refreshing scents and skin benefits, and in cleaning products for their anti-microbial properties. Furthermore, their therapeutic potential has led to their inclusion in pharmaceutical and nutraceutical products. This review underscores the multifaceted role and economic significance of Citrus volatile organic compounds, advocating for continued research and technological advances to fully harness their benefits in health, industry, and sustainability.
Co-Authors Fatia Zahra Kharina Tambunan Nerdy Nerdy Refi Bahrianur Said Haikal Alfajar Shadiq Suwailim Sumardi Sumardi Syarifah Nadia Tari Putri Utami Rizki Tedy Kurniawan Bakri