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All Journal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Majalah Info Sains
Natanel, Andri
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology

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Uji Aktivitas Repelan Minyak Atsiri Daun Jeruk Purut (Citrus hystrix Dc) Terhadap Nyamuk Natanel, Andri; Pareta, Douglas N.; Ginting, Amal R.; Tulandi, Selvana S.
Majalah INFO Sains Vol 5 No 2 (2024): Oktober 2024
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Kristen Indonesia Tomohon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jis.v5i2.75

Abstract

Penelitian ini bertujuan untuk menguji aktivitas repelan minyak atsiri daun jeruk purut (Citrus hystrix DC) terhadap nyamuk Aedes aegypti dengan basis minyak kelapa murni (VCO). Metode penelitian yang digunakan adalah eksperimental laboratorium dengan rancangan acak lengkap (RAL) yang melibatkan lima perlakuan konsentrasi (0%, 12,5%, 25%, 50%, dan kontrol positif Autan). Hasil penelitian menunjukkan bahwa minyak atsiri daun jeruk purut memiliki aktivitas repelan yang signifikan terhadap nyamuk, dengan konsentrasi 50% menunjukkan daya proteksi tertinggi sebesar 92,30%. Analisis statistik menggunakan uji Uji statistik ANOVA dan tukey HSD menunjukkan perbedaan signifikan antar kelompok perlakuan (p<0,05). Kesimpulan dari penelitian Minyak atsiri jeruk purut berpotensi dikembangkan sebagai alternatif repelan alami yang aman dan efektif serta ramah lingkungan.
Inhibitory Test of Scleria sumatrensis Stem Extract against Propionibacterium acnes Bacteria in Vitro Untu, Sonny D.; Pareta, Douglas N.; Tulandi, Selvana S.; Kanter, Jabes W.; Natanel, Andri
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 8 No. 1 (2025): April 2025
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v8i1.505

Abstract

This study aims to test the antibacterial activity of Scleria sumatrensis extract against Propionibacterium acnes, a bacteria that causes acne. Extraction was carried out using the maceration method using 96% ethanol, and the antibacterial activity test was carried out using the diffusion method using a concentration of 100–500 ?g/disc. The results showed that the extract provided moderate antibacterial activity at a concentration of 100 ?g/disc and increased to strong at a concentration of 200–500 ?g/disc. S. sumatrensis extract contains secondary metabolite compounds such as phenolics, flavonoids, alkaloids, tannins, steroids, and terpenoids that play a role in inhibiting the growth of P. acnes through various mechanisms, including cell membrane damage, inhibition of protein synthesis, and disruption of bacterial metabolism. Based on the results of the study, S. sumatrensis extract has the potential as a natural antibacterial alternative for acne treatment without significant side effects or the risk of antibiotic resistance.
Co-Authors Douglas N. Pareta Ginting, Amal R. Jabes Wolter Kanter Sonny Untu Tulandi, Selvana Stien