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All Journal Biology, Medicine, & Natural Product Chemistry Indonesian Journal of Science and Mathematics Education
Ayudia, Indah
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Biochemistry, Genetics & Molecular Biology Education Mathematics Medicine & Pharmacology Public Health

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Animation videos to enhance senior high school students' motivation in learning chemistry: A learning media in inclusive schools Ayudia, Indah; Kamaludin, Agus
Indonesian Journal of Science and Mathematics Education Vol. 7 No. 1 (2024): Indonesian Journal of Science and Mathematics Education
Publisher : Universitas Islam Negeri Raden Intan Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/ijsme.v7i1.21261

Abstract

The instructional media in inclusive schools has not been fully developed inclusively in line with the potential and needs of students with disabilities. This research aims to develop inclusive instructional animation videos on chemical bonding to enhance the learning motivation of tenth-grade senior high school students. This study adopts a research and development (R and D) approach using the ADDIE development model. Research instruments utilized include quality assessment sheets and student responses. Evaluation results from subject matter experts, media experts, reviewers, and student responses indicate that the video is highly effective and well-received, with a high percentage of perceived appropriateness. Consequently, this video is deemed suitable as an alternative instructional medium in inclusive classrooms, supporting students' understanding of chemical bonding and enhancing learning motivation, especially for students with disabilities. Additionally, this research highlights the potential of utilizing Artificial Intelligence (AI) in developing inclusive instructional media.
Phytochemical Profile, Antioxidant Activity, and Brine Shrimp Lethality Test of Thyrsostachys siamensis (Siamese Bamboo) Leaf Extracts Hidayah, Muhamad Aditya; Ayudia, Indah; Tunjungsari, Gerda Pintoko; Fikroh, Retno Aliyatul; Ahmad, Alfandi
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.379-389

Abstract

Cancer and oxidative-stress–related disorders continue to rise globally, driving interest in plant-based antioxidants with concurrent cytotoxic potential. This study aimed to characterize the phytochemical profile, antioxidant activity, and brine shrimp (Artemia salina) lethality of Thyrsostachys siamensis (Siamese bamboo) leaf extracts obtained with solvents of increasing polarity (n-hexane, chloroform, acetone, ethyl acetate, methanol, ethanol, and water). Ethanol appears as the most effective solvent for T. siamensis, combining a solid extraction yield (7.78%) with the richest phytochemical profile (positive for alkaloids, flavonoids, saponins, tannins, and phenolics). This broad chemical recovery corresponds to the strongest bioactivity, shown by its lowest IC50 (91.48 ± 0.12 µg/mL) and LC50 (80.78 ± 0.62 µg/mL). Acetone (6.42%) and ethyl acetate (5.11%) offer moderate yields and selective enrichment of semi-polar constituents, reflected in intermediate IC50 values (144–150 µg/mL) and LC50 values (273–350 µg/mL). In contrast, hexane despite providing the highest mass recovery (11.34%) contains mainly non-phenolic components and shows weak biological activity (IC50 200.52 ± 0.38 µg/mL, LC50 620.06 ± 0.76 µg/mL). Chloroform, with limited phytochemical content, yields the poorest performance (IC50 238.30 ± 1.56 µg/mL, LC50 926.40 ± 4.27 µg/mL).
Co-Authors Agus Kamaludin, Agus Ahmad, Alfandi Fikroh, Retno Aliyatul Hidayah, Muhamad Aditya Tunjungsari, Gerda Pintoko