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All Journal Journal of Epidemiology and Public Health Psychiatry Nursing Journal (Jurnal Keperawatan Jiwa)
Ana, Kartika Febry
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Health Professions Nursing Public Health

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Urine Test Accuracy of Lipoarabinomannan in Diagnosing Pulmonary Tuberculosis in Adults: Meta-Analysis Fauziy, Jihan Nafisah; Ana, Kartika Febry
Journal of Epidemiology and Public Health Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.01.04

Abstract

Background: Mycobacterium tuberculosis (Mt) requires non-sputum-based screening that can identify it with high sensitivity and specificity. Lipoarabinomannan (LAM) is a diagnosis of active tuberculosis (TB) in samples such as urine, both by complex laboratory-based testing and in simple treatment tools. The purpose of this study was to determine the accuracy of the Lipoarabinomannan urine test in diagnosing TB in adults. Subjects and Method: This study is a meta-analysis study with PICO covering, population= adult age with suspected tuberculosis (TB). Intervention= lipoarabinomannan urine test. Comparison: no lipoarabinomannan urine test was performed. Outcome: sensitivity and specificity. Using the PRISMA flowchart guidelines. The articles used were conducted between 2012-2021 from the PubMed, Google Scholar, MedLine, and Science Direct databases. The keywords used in the article search were “Lipoarabinomannan” AND “LAM” OR “Adult” AND “Patient” OR “Diagnosis” OR “Pulmonary tuberculosis”. Based on the database, there were 9 articles that matched the inclusion criteria. Data analysis using the RevMan 5.3 application. Results: A total of 9 cohort studies with a total of 3,069 patients from South Africa (Cape Town, KwaZulu-Natal, Zimbabwe), East Africa (Kenya, Malawi, Tanzania, Uganda, Zambia), West Africa (Ghana) and South America (Peru) were selected for the study. systematic review and meta-analysis. A meta-analysis of 9 cohort studies showed that the lipoarabinomannan urine test had 2.89 times the accuracy or sensitivity in diagnosing TB compared to no lipoarabinomannan urine test (aOR= 2.89; 95% CI= 2.30 to 3.63; p= 0.160), but was not statistically significant. Conclusion: The lipoarabinomannan urine test improves accuracy in diagnosing pulmonary tuberculosis in adults but is not statistically significant. Keywords: lipoarabinomannan, LAM, adult, patient, diagnosis, pulmonary tuberculosis. Correspondence: Jihan Nafisah Fauziy. Masters Program in Public Health. Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: jihannafisah321@gmail.com. Mobile: 082135798209.
The Community Attitudes And Behavior Towards People Living With Mental Illness: A Descriptive Study Ana, Kartika Febry
Psychiatry Nursing Journal (Jurnal Keperawatan Jiwa) Vol. 5 No. 1 (2023): March 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/pnj.v5i1.35187

Abstract

Introduction: Mental health is still a significant problem in the world, because health is not only seen as free from disease but also includes all aspects of human life, physical, emotional, social and spiritual. The purpose of this study is to describe the attitudes and behavior of individuals in patients with mental disorders in the community. Method: This study used a quantitative descriptive design. The population in this study were people in three RWs in one urban village of Surakarta with a total of 4,465 people. The sample used in this study was 99 respondents using a simple random sampling. The analysis used is univariate analysis with a central tendency. The instrument used individual characteristics, attitudes and behavior towards mental patients Results: Based on the results of research on 99 respondents, it was found that the characteristics of the majority of respondents were female (64,6%), age 36-45 years (38,4%), being high school education level (53,5%) and the majority working as laborers (23,2%). The attitude of respondents to patients with mental disorders is negative or less supportive (52,52%), while the behavior of respondents to patients with mental disorders is considered less good (79,8%). Conclusions: The community still had negative attitude and poor behavior toward people living with mental illness. This result indicated the need for intervention and promotion about mental illness in the community setting.
Urine Test Accuracy of Lipoarabinomannan in Diagnosing Pulmonary Tuberculosis in Adults: Meta-Analysis Fauziy, Jihan Nafisah; Ana, Kartika Febry
Journal of Epidemiology and Public Health Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.31 KB) | DOI: 10.26911/jepublichealth.2022.07.01.04

Abstract

Background: Mycobacterium tuberculosis (Mt) requires non-sputum-based screening that can identify it with high sensitivity and specificity. Lipoarabinomannan (LAM) is a diagnosis of active tuberculosis (TB) in samples such as urine, both by complex laboratory-based testing and in simple treatment tools. The purpose of this study was to determine the accuracy of the Lipoarabinomannan urine test in diagnosing TB in adults. Subjects and Method: This study is a meta-analysis study with PICO covering, population= adult age with suspected tuberculosis (TB). Intervention= lipoarabinomannan urine test. Comparison: no lipoarabinomannan urine test was performed. Outcome: sensitivity and specificity. Using the PRISMA flowchart guidelines. The articles used were conducted between 2012-2021 from the PubMed, Google Scholar, MedLine, and Science Direct databases. The keywords used in the article search were “Lipoarabinomannan” AND “LAM” OR “Adult” AND “Patient” OR “Diagnosis” OR “Pulmonary tuberculosis”. Based on the database, there were 9 articles that matched the inclusion criteria. Data analysis using the RevMan 5.3 application. Results: A total of 9 cohort studies with a total of 3,069 patients from South Africa (Cape Town, KwaZulu-Natal, Zimbabwe), East Africa (Kenya, Malawi, Tanzania, Uganda, Zambia), West Africa (Ghana) and South America (Peru) were selected for the study. systematic review and meta-analysis. A meta-analysis of 9 cohort studies showed that the lipoarabinomannan urine test had 2.89 times the accuracy or sensitivity in diagnosing TB compared to no lipoarabinomannan urine test (aOR= 2.89; 95% CI= 2.30 to 3.63; p= 0.160), but was not statistically significant. Conclusion: The lipoarabinomannan urine test improves accuracy in diagnosing pulmonary tuberculosis in adults but is not statistically significant. Keywords: lipoarabinomannan, LAM, adult, patient, diagnosis, pulmonary tuberculosis. Correspondence: Jihan Nafisah Fauziy. Masters Program in Public Health. Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: jihannafisah321@gmail.com. Mobile: 082135798209.
Co-Authors Fauziy, Jihan Nafisah