Kadek Ardhyani Widya Ningrum
Universitas Pembangunan Nasional Veteran Jawa Timur

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THE ROLE OF FERMENTED FOODS IN REGULATING GUT MICROBIOTA AND MENTAL HEALTH: A Literature Review Kadek Ardhyani Widya Ningrum; Aristanto Prambudi
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 12 (2025): Journal of Diverse Medical Research : Medicosphere 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i12.301

Abstract

Background: Scientifically, fermentation is the process by which microorganisms convert sugar into alcohol and organic acids, which extends the shelf life of food. Today, the field of Nutritional Psychiatry has emerged to identify food components that are important for mental health, emphasizing that the complex interaction between nutrition and brain function highlights the need for a multidisciplinary approach. Objective: To explore the role of fermentation-based diets in regulating gut microbiota and their impact on mental health. Methods: The research method used was a literature review, with five journals reviewed. Results: Based on the five research journals reviewed, the main findings centered on the crucial and comprehensive relationship between gut microbiota, nutrition (diet), and mental health. The first journal introduced psychobiotics, specific live microorganisms that provide therapeutic benefits for mental disorders by increasing the production of important neurotransmitters such as dopamine and serotonin in the gut. The second and fourth journals explicitly show a strong correlation between a healthy diet and mental well-being. The third journal specifically discusses the role of fermented foods in Nutritional Psychiatry. The fifth journal also discusses lifestyle and nutritional neuroscience related to mental health. Conclusion: There is a close relationship between gut microbiota, diet, and mental health, which indicates the potential of nutritional and psychobiotic interventions in the prevention and treatment of mental disord
Hormonal and Psychological Factors in The Management of Rheumatoid Arthritis in Women : Literature Review Kadek Ardhyani Widya Ningrum; Fachrizal Arfani Prawiragara; Fitria Kusuma Wardhani
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 6 (2024): J Divers Med Res
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i3.36

Abstract

Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation of the joints and can lead to systemic complications. The prevalence of RA ranges from 0.5% to 1% of the global population, with a higher incidence in women than men. This literature review aims to analyze current research related to hormonal and psychological factors that influence the management of RA in women. Methods. A search was conducted through databases such as PubMed, Scopus, Google Scholar, and ScienceDirect with the criteria of articles published within the last five years. Discussion. Results suggest that hormonal fluctuations, such as estrogen and progesterone, may affect RA symptoms, especially during pregnancy and menopause. In addition, psychological factors, including stress and depression, have a significant impact on quality of life and pain perception in RA patients. Thus, the management of RA requires a comprehensive approach that considers both hormonal and psychological factors. Conclusion. This review emphasizes the importance of patient education as well as recommendations for further research into the specific role of hormones in RA pathogenesis and the development of more integrated psychological interventions. Keywords. Rheumatoid arthritis, autoimmune disease, hormonal, psychological, quality of life