Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Social Landscape Journal Jurnal Pranata Biomedika
Annisa, Sitti
Unknown Affiliation
Education Environmental Science Medicine & Pharmacology Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS AUDIO VISUAL MENGGUNAKAN APLIKASI FILMORA PADA MATA PELAJARAN GEOGRAFI MATERI FLORA DAN FAUNA DI INDONESIA DAN DUNIA SMA NEGERI 1 DULUPI annisa, sitti; Lihawa, Fitryane; Mohamad, Nurdin
Social Landscape Journal Vol 5, No 1 (2024): March
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56680/slj.v5i1.58700

Abstract

This research is research into the development of audio-visual based learning media using the Filmora application. This research aims to produce audio-visual based learning media using the Filmora application on flora and fauna material in Indonesia and the world. This research uses a development research method using the ADDIE model as an approach in compiling learning media. In this research there are 5 stages, namely the analysis stage, design stage, development stage, implementation stage and evaluation stage. The results of the development research were obtained from the validator assessment results which showed that this learning media was declared suitable for use and very valid. The assessment given to each statement is as follows: from product design expert validation it is declared very valid with a rating result of 84%, from material/content experts it is declared very valid with a rating result of 91.1% and the learning expert in this case is a geography teacher declared very valid with a rating result of 90.3% and the average student response to learning media was 89.1%, which means it was classified as very good media. The conclusion of this research is that audio-visual based learning media using the Filmora application developed by researchers is declared suitable for use in the learning process.
EFEK METFORMIN TERHADAP KARAKTERISTIK INSULA PANKREATIKA MODEL TIKUS OBESITAS Annisa, Sitti; Pakaya, David
Jurnal Pranata Biomedika Vol 4, No 1: Maret 2025
Publisher : Universitas Katolik Soegijapranata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/jpb.v4i1.12306

Abstract

Latar belakang : Peradangan kronis seperti pada obesitas dapat memicu kematian sel-sel pada dan merusak struktur insula pankreatika. Metformin memiliki efek anti peradangan yang berfungsi mengendalikan kerusakan insula pankreatika pada obesitas.Tujuan penelitian : mengetahui efek metformin terhadap karakteristik insula pankreatika pada model tikus obesitas.Metode : Menggunakan eksperimental study dengan rancangan post test only controlled  design dengan pendekatan kualitatif dan kuantitatif. Penelitian ini menggunakan 15 ekor tikus putih galur wistar jantan berusia 10-12 minggu, berat badan (BB) 200-250 gram. Tikus dibagi dalam 3 kelompok perlakuan; K1: kontrol normal; K2: model obesitas; K3: model obesitas + terapi metformin 250mg/kgBB. Tikus dimodifikasi menjadi model obesitas dengan pemberian high fat diet (HFD). Dilakukan pengukuran BB secara berkala. Gambaran histopatologi insula pankreatika didapatkan dari pewarnaan Hematoksilin eosin (HE) pada 5 lapang pandang yang dipilih secara acak dan tidak tumpang tindih dengan menggunakan mikroskop cahaya Olympus CX23 perbesaran 400x. Hasil gambar dikuantifikasi menggunakan perangkat lunak ImageJ. Data dianalisis dengan GrapPhard Prism 8.0.0 menggunakan uji non parametrik Kruskal-Wallis. Hasil : Berat badan kelompok K3 yang diterapi metformin lebih rendah dari K1 dan K2. Morfologi insula pankreatika menunjukkan perbedaan bermakna (p=0,002).  Morfometri insula pankreatika menunjukkan perbaikan pada diameter dan perimeter tetapi tidak bermakna secara statisitk (p=0,1226). Jumlah insula pankreatika tidak dipengaruhi (p=0,19).Kesimpulan : Metformin mampu menurunkan BB dan mampu memperbaiki morfologi insula pankreatika, namun tidak pada morfometri dan jumlah insula pankreatika pada tikus model obesitas.
Co-Authors David Pakaya Fitryane Lihawa Mohamad, Nurdin