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All Journal ALCHEMY Jurnal Penelitian Kimia FaST : Jurnal Sains dan Teknologi
Antonius Herry Cahyana
Universitas Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Energy Environmental Science Materials Science & Nanotechnology

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Phytochemical and Pharmacological Properties of Myristica fragrans Leaves Houtt. Ariyanti Saputri; Sofa Fajriah; Antonius Herry Cahyana
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93701.17-32

Abstract

Myristica fragrans is a widely distributed plant that grows well in Indonesia. This plant, also known as nutmeg, has been used in various fields such as food, aromatherapy, and other industries. Research on nutmeg plants has been widely conducted, but most of it discusses the seeds and mace of nutmeg. However, research on nutmeg leaves is still limited, with only a few studies to be discussed in this review article. This article provides an overview of the chemical compounds, bioactivity, and toxic effects of essential oils and nutmeg leaf extracts collected from the latest literatures (2014–2024). This article aims to draw more attention to nutmeg leaf research to be developed into natural-based medicinal products. Some compounds contained in nutmeg leaves include dihydrokaempferol, myristicin, 1,1,3,3,5,5,7,7,9,9,11,11,13,13-tetradecamethylheptasiloxane, 2,2-dimethyl-1-decanol, bis(2-ethyl hexyl) phthalate, and 9-dodecane-1-al, gamma-terpinene; caryophyllene and others. In addition, nutmeg leaf compounds also have various interesting bioactivities such as antibacterial, antifungal, antioxidant, larvicidal, and good cytotoxic activity. Overall, nutmeg leaves show great potential as a raw material for medicine. The results of this study also show various types of secondary metabolites with interesting bioactivities that require further study.
AKTIVITAS ANTIOKSIDAN NANOPARTIKEL SENG OKSIDA PADA DAUN DAN BUAH PIRDOT (Saurauia vulcani Korth.) [ANTIOXIDANT ACTIVITY OF ZINC OXIDE NANOPARTICLES ON THE LEAVES AND FRUIT OF PIRDOT] (Saurauia vulcani Korth.) Lukas Hotma Parulian Lumantobing; Ratna Handayani; Antonius Herry Cahyana
FaST : Jurnal Sains dan Teknologi Vol. 8 No. 2 (2024): NOVEMBER
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/jstfast.v8i2.8998

Abstract

One of the potential local sources of Indonesia for nanoparticle synthesis is pyrdot (Saurauia vulcani Korth.). This study aims to synthesize zinc oxide nanoparticles with pyrdot leaf and fruit extracts by maceration. Total phenolic testing using the Folin-Ciocalteau method, antioxidant activity using the DPPH method. Antioxidant activity with IC50 of 0.891 ± 0.045 (leaf ZnONPs), 2.181 ± 0.167 (leaf extract), 2.945 ± 0.009 (fruit ZnONPs), and 4.017 ± 0.277 (fruit extract) respectively. ZnoNPs were subjected to morphological testing using SEM and TEM methods as well as particle size testing with the general results that the nanoparticles obtained met the requirements as a nanoparticle in terms of particle size, with leaf ZnONPs generally having a smaller particle size than fruit, although morphologically they are generally irregular in shape.Bahasa Indonesia Abstract:Salah satu sumber lokal Indonesia yang potensial untuk sintesis nanopartikel adalah pirdot (Saurauia vulcani Korth.). Penelitian ini bertujuan untuk mensintesis nanopartikel seng oksida dengan ekstrak daun dan buah pirdot dengan maserasi. Pengujian total fenolik menggunakan metode Folin-Ciocalteau, aktivitas antioksidan menggunakan metode DPPH. Aktivitas antioksidan dengan IC50 masing-masing sebesar 0,891 ± 0,045 (ZnONPs daun), 2,181 ± 0,167 (ekstrak daun), 2,945 ± 0,009 (ZnONPs buah), dan 4,017 ± 0,277 (ekstrak buah). ZnoNPs dilakuan pengujian morforlogi dengan metode SEM dan TEM serta pengujian ukuran partikel dengan hasil secara umum bahwa nanopartikel yang didapat memenuhi syarat sebagai sebuah nanopartikel dalam hal ukuran partikel, dengan ZnONPs daun secara umum memiliki ukuran partikel lebih kecil dari buah, meskipun secara morfologi pada umumnya berbentuk tidak beraturan.
Co-Authors Ariyanti Saputri Handayani, Ratna Lukas Hotma Parulian Lumantobing Sofa Fajriah