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All Journal Indonesian Journal of Cardiology YARSI Medical Journal
Purwowiyoto, Sidhi Laksono
The Indonesian Heart Association
Health Professions Medicine & Pharmacology

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Kardiomiopati Dilatasi pada Pasien HIV-AIDS Purwowiyoto, Sidhi Laksono
Jurnal Kedokteran YARSI Vol 26, No 1 (2018): JANUARI - APRIL 2018
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1521.336 KB) | DOI: 10.33476/jky.v26i1.363

Abstract

The heart and great vessels are not the sites most frequently affected by opportunistic infections and neoplastic processes in patients with acquired immune deficiency syndrome (AIDS). HIV-related disease is now recognized as an important cause of dilated cardiomyopathy, with a prevalence of 8%–30%. Patients with HIV-infection and dilated cardiomyopathy have a much worse prognosis than those with idiopathic dilated cardiomyopathy. Cardiac involvement in HIV represents a pathophysiologic, diagnostic and therapeutic challenge for cardiologists. This review describes pathophysiology, diagnosis, treatment and prognosis of HIV- dilated cardiomyopathy.
Obstructive Sleep Apnea dan Gagal Jantung Purwowiyoto, Sidhi Laksono
Jurnal Kedokteran YARSI Vol 25, No 3 (2017): SEPTEMBER - DESEMBER 2017
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (686.544 KB) | DOI: 10.33476/jky.v25i3.364

Abstract

Obstructive sleep apnea (OSA) is a part of sleep-disordered breathing which is commonly found in the population of heart failure. Epidemiological studies have shown significant independent associations between OSA and heart failure. OSA plays an important role in the pathogenesis and progression of heart failure. Several pathogenesis are the mechanical effect, activation of sympathetic, inflammation process, and endothelial dysfunction. These can impair myocardial contractility and cause development and progression of heart failure. However, the prevalence OSA is only the “tip of the iceberg” due to the difficulty in diagnosis. Most of OSA patients, particularly in the heart failure population, have no complaint of the sleepiness. 
CT-FFR: Clinical Application Purwowiyoto, Sidhi Laksono
Indonesian Journal of Cardiology Vol 39 No 1 (2018): January - March 2018
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v39i1.796

Abstract

Invasive fractional flow reserve (FFR) is the gold standard for guiding decision making to identify patients who would benefit from revascularization. Now, computed tomography can also do that by using computational fluid dynamics to calculate fractional flow reserve values from coronary CT angiography image data sets, known as CT-FFR. CT-FFR as an alternative method beside invasive FFR enables the identification of lesion-specific in coronary tree noninvasively. CT-FFR has showed significant improvement in specificity and positive predictive value and decreasing the frequency of using invasive coronary angiography.   Abstrak Pemeriksaan invasif fractional flow reserve (FFR) adalah standar emas untuk memandu pengambilan keputusan dalam mengidentifikasi pasien apakah yang mendapat manfaat dari revaskularisasi. Sekarang, computed tomography juga dapat melakukannya dengan menggunakan dinamika cairan terkomputasi untuk menghitung fractional flow reserve dari kumpulan data gambar angiografi koroner CT, yang dikenal sebagai CT-FFR. CT-FFR sebagai metode alternatif selain FFR invasif memungkinkan identifikasi spesifik lesi pada koroner secara non-invasif. CT-FFR telah menunjukkan peningkatan yang signifikan pada spesifisitas dan nilai prediksi positif dan penurunan frekuensi penggunaan angiografi koroner invasif.
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