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All Journal The Health Researchers Journal
Shofiy, Alifya Rayyani
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Public Health

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ANTI-INFLAMMATORY EFFECTS OF Graptophyllum pictum (L.) GRIFF EXTRACT IN PRECLINICAL RATS HIND-PAW EDEMA MODELS: A LITERATURE REVIEW Shofiy, Alifya Rayyani; Makiyyah, Feda Anisah
The Health Researcher's Journal Vol. 2 No. 01 (2025): The Health Researchers Journal
Publisher : The SDGS Forum Communication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.00000/37a33t66

Abstract

Graptophyllum pictum (L.) Griff or daun ungu is a common medical plant in Indonesia that possesses many promising medical properties, including anti-inflammation. This review aims to discuss the anti-inflammatory effects of Graptophyllum pictum (L.) Griff extract in preclinical hind-paw edema animal models. Through literature search and analyze based on keywords, PICO, inclusion, and exclusion criteria, a total of four studies were included in this review. As a result, ethanol extract of Graptophyllum pictum (L.) Griff shows anti-inflammatory effects significantly reducing the volume of edema and having high anti-inflammatory power by inhibition of the arachidonic inflammatory pathway. Therefore, these preclinical test studies confirmed the anti-inflammatory effects of Graptophyllum pictum (L.) Griff. However, further studies and human trials are required to confirm the efficacy and develop a  standardized formula for Graptophyllum pictum (L.) Griff.
Co-Authors Makkiyah, Feda Anisah