Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Chemistry
Do, Nga Hoang Nguyen
Unknown Affiliation
Chemical Engineering, Chemistry & Bioengineering Chemistry

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Effectiveness of Cobalt-Doped Biochar Derived from Durian Shell for Degradation of Rhodamine B Trinh, Anh Mai Hoang; Le, Thinh Phu; Tran, Khoi Anh; Do, Nga Hoang Nguyen; Le, Kien Anh; Tran, Viet Tan; Le, Phung Kim
Indonesian Journal of Chemistry Vol 25, No 2 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.99181

Abstract

The global discharge of dye-contaminated effluent into the environment has garnered considerable public attention, and removing the organic pollutants from wastewater is of great importance. Durian shell, a major by-product of Asia countries, is one of the primary causes of environmental issues. To address these current issues, the development of efficient and eco-friendly biomass-derived catalysts that activate advanced oxidation processes (AOP) stands out as a crucial technology for treating organic pollutants in water. In this study, cobalt-doped biochar composites (CoC-n) were synthesized using solvothermal and calcination techniques, with durian shell biomass serving as the precursor material. The obtained CoC-n treated under various calcination temperatures analyzed via SEM, EDS, XRD, and FTIR techniques, which were used for efficient peroxymonosulfate (PMS) activation for up to 92% and 58.98–74.30% RhB (25  and 75 mg/L, respectively) degradation in 30 min. The quenching test performed on the CoC-350/PMS system revealed that RhB degradation involves sulfate (SO4•−), hydroxyl (OH•), and singlet oxygen (1O2) in RhB degradation, with SO4•− and 1O2 being the primary components. The cobalt-doped biochar from durian shells is considered a novel and promising candidate for the eradication of dye-contaminated effluent applications.
Prolonged Release of Anti-inflammatory Diclofenac Sodium from In Situ Loaded Thermosensitive Chitosan Hydrogels for Localized Applications Do, Nga Hoang Nguyen; Le, Ha Vu; Nguyen, Khoa Dang; Ha, Anh Cam
Indonesian Journal of Chemistry Vol 25, No 5 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.106833

Abstract

Previous work developed a thermosensitive hydrogel from chitosan (CS) and β-glycerophosphate (GP) loaded with diclofenac sodium (DIC) using a post-loading method. The hydrogel as a wound dressing exhibited burst release of DIC within 5 h, rendering it suitable for immediate anti-inflammatory treatment. For the first time, the in situ loading method has been applied to synthesize an injectable CS/GP hydrogel for prolonged DIC release. The optimal synthesis condition is at 1.0 w/v% CS (high molecular weight of 324 kDa) and 4.0 w/v% GP, yielding the hydrogel capable of sol-gel transition at 37 °C. The porous structure of the hydrogels is filled with DIC, ensuring efficient drug entrapment. The hydrogels demonstrate prolonged DIC release over 7 days, achieving a cumulative drug release (CDR) ranging from 62.39 to 80.51%. At an initial DIC loading of 3000 µg/mL, the hydrogel maintains a drug concentration above 10 µg/mL after 6 days of release. DIC release kinetics are temperature-dependent, with a higher CDR at 39 °C (simulating an inflammatory condition) than 37 °C (normal body temperature), and governed by drug diffusion and hydrogel network swelling. This study provides a novel approach for synthesizing an injectable temperature-responsive CS hydrogel for local anti-inflammatory DIC delivery.
Co-Authors Ha, Anh Cam Le, Ha Vu Le, Kien Anh Le, Phung Kim Le, Thinh Phu Nguyen, Khoa Dang Tran, Khoi Anh Tran, Viet Tan Trinh, Anh Mai Hoang