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All Journal The Journal of Society Medicine (JSOCMED)
Nasution , Ali Nafiah
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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The Relationship Between Low-Density Lipoprotein Cholesterol and Coronary Artery Calcium Score in Patients with Chronic Coronary Syndrome Without Diabetes Mellitus at RSUP Haji Adam Malik Medan Muslim, Suci Asriri Pradina; Lubis , Hilfan Ade Putra; Nasution , Ali Nafiah
Journal of Society Medicine Vol. 4 No. 3 (2025): March
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i3.203

Abstract

Introduction: Chronic Coronary Syndrome (CCS) is the most common symptom of ischemic heart disease and is a major cause of morbidity and mortality worldwide. One of the associated risk factors for coronary heart disease events is Low Density Lipoprotein Cholesterol (LDL-C) through the process of atherosclerosis. Computed Tomography Coronary Artery (CTCA) is an examination that can be performed to assess atherosclerotic plaques and Coronary Artery Calcium Score (CAC Score). This study was conducted to assess the relationship between LDL and CAC Score in CCS patients. Methods: This study is an observational analytical study involving 300 patients diagnosed with CCS during the period from March 1, 2023, to March 31, 2024, at RSUP H. Adam Malik Medan. All involved patients underwent LDL examination and CTCA examination as well as CAC Score measurement. Patient characteristics, disease history, and risk factors were also recorded. Results: There was a significant relationship between LDL levels and CAC Score (P value: 0.008; OR: 1.91 (CI: 1.184-3.1). Among the patient characteristics in this study, the strongest protective factor was female gender (P value: <0.01; OR: 0.228 (CI: 0.119-0.437)), and the strongest risk factor was patients with hypertension (P value: 0.017; OR: 1.97 (CI: 1.119-3.484). Conclusion: LDL can increase CAC Score in CCS patients.
Comparison of C2HEST and MC2HEST Scores as Predictors of New-Onset Atrial Fibrillation in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention at Haji Adam Malik Hospital Medan Hanifah, Putri Vidya; Nasution , Ali Nafiah; Putra , Hilfan Ade
Journal of Society Medicine Vol. 4 No. 4 (2025): April
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i4.201

Abstract

Introduction: To evaluate whether the C2HEST and mC2HEST scores have good ability as predictors of new-onset atrial fibrillation in patients with acute coronary syndrome undergoing percutaneous coronary intervention at HAM Hospital Medan. Method: This study is a retrospective cohort study. Retrospective data were collected by total sampling from all medical records of ACS patients at Adam Malik Hospital from January to September 2024. Prospective data were collected consecutively until the minimum sample size was met. Samples included in the research analysis were those that met the inclusion criteria without exclusion criteria. Results: As a predictive method, the mC2HEST score is as good as the C2HEST score, with AUCs of 0.713 and 0.728, respectively. The cut-off point obtained is the same for both scores, which is >3. The C2HEST score has a sensitivity of 73.7%, specificity of 52.6%, while the mC2HEST score has a sensitivity of 78.9%, specificity of 55.1%. The total number of samples that met the criteria was 108 patients. Patients with new-onset atrial fibrillation numbered 19 (17.6%). The youngest patient was 30 years old and the oldest was 81 years old. The average age in patients with new-onset atrial fibrillation was 67 years and without new-onset atrial fibrillation was 57 years. This study also yielded a new scoring system as an alternative predictive method. Conclusion: The mC2HEST score is as good as the C2HEST score as a predictor of new-onset atrial fibrillation in patients with acute coronary syndrome undergoing percutaneous coronary intervention at HAM Hospital Medan.
Co-Authors Hanifah, Putri Vidya Lubis , Hilfan Ade Putra Muslim, Suci Asriri Pradina Putra , Hilfan Ade