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Comparative Analysis of Erythrocyte, Leukocyte, and Platelet Indices through Examinations using Sysmex XN-3000 and Yumizen H2500 in Clinical Practice Wardani, Yuniar Putri; Indrasari, Yulia Nadar; Amrita, Putu Niken Ayu; Fuadi, Muhamad Robi'ul
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 1 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i1.65391

Abstract

Introduction: Examining erythrocyte, leukocyte, and platelet indices is critical for diagnosis, disease management, therapy selection, and monitoring. It is imperative to evaluate the hematology analyzer used for a complete blood examination, as each device possesses distinct specifications, methods, and technologies. This study aimed to compare complete blood count parameters, specifically the erythrocyte, leukocyte, and platelet indices, using Sysmex XN-3000 and Yumizen H2500. Methods: This cross-sectional study used blood samples from adult outpatients aged >18 years at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Samples were collected using purposive sampling, resulting in 100 blood specimens for complete blood count analysis. The examined variables included erythrocyte, leukocyte, and platelet indices, which were compared across two different instruments, i.e., Sysmex XN-3000 and Yumizen H2500. The data were analyzed using either the Spearman or Pearson correlation test (p<0.05). The Bland-Altman plotting was employed to assess the differences between variables, with a minimum of five agreed-upon outliers. Results: Significant correlations were observed across all parameters, except for the mean corpuscular hemoglobin concentration (MCHC), which showed limited agreement in the Bland-Altman analysis. The Pearson and Spearman analyses revealed a significant correlation in the parameters of erythrocytes (0.00), leukocytes (0.00), and platelets (0.00). The Bland-Altman plot indicated seven outliers in the average MCHC values from the two analyzers, demonstrating insufficient agreement. Conclusion: There is significant agreement and correlation in the erythrocyte, leukocyte, and platelet indices from both analyzers. This finding affirms the compatibility of both instruments for clinical use, with caution advised when interpreting MCHC values.   Highlights: 1. This study evaluated the validity of different hematology analyzers for complete blood count examinations in medical laboratories, a topic that has rarely been discussed in detail. 2. The results of this study are expected to contribute to the quality improvement of medical laboratory technologies in Indonesia.
PARENTAL BELIEF ON HPV VACCINATION ACCEPTANCE: A STUDY ON FEMALE STUDENT AT PRIMARY SCHOOL IN SURABAYA Nasywa, Shofia Ayu Hilda Atha; Wardani, Yuniar Putri; Herawati, Jenny Dwi; Nurbaittrisna, Fatya; Artanti, Kurnia Dwi
Jurnal Biometrika dan Kependudukan Vol. 14 No. 2 (2025): JURNAL BIOMETRIKA DAN KEPENDUDUKAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbk.v14i2.2025.179-187

Abstract

Cervical cancer is the second leading cause of cancer-related deaths and one of the major health financing burdens in Indonesia. The Global Cancer Observatory reported 36,633 new cases of cervical cancer in Indonesia in 2020, with mortality rates on the rise. The primary cause, accounting for 99.7% of cases, is the oncogenic human papillomavirus (HPV). HPV vaccination was expanded as a national program through the School Immunization Month in 2023. However, evaluations reveal ongoing parental resistance, preventing vaccination coverage targets from being met. The purpose of this study is to identify related factors to parental perceptions toward the acceptance or rejection of HPV vaccination. This research uses quantitative methods. Data analysis was carried out by displaying quantitative statistical results using the Chi Square SPSS test from 100 respondents. As a result, no association was found between the Health Believe Model (HBM) theory among parents and the vaccination status of elementary school female student aged 11-12 years in Surabaya. There are other factors that may influence the confidentiality of protection against the HPV vaccine, such as misinformation, the influence of social norms, and the level of trust in the government health system. In addition, further research is needed to investigate and explore other factors outside the Health Belief Model theory that may be involved in HPV vaccination coverage.