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All Journal Jurnal Buana Farma Jurnal Farmasi Indonesia
Khoerunnisa, Rita
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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REVIEW ARTIKEL: SISTEM PENGHANTARAN OBAT SNEEDS (Self-Nanoemulsifying Drug Delivery System) DALAM FORMULASI OBAT HERBAL Khoerunnisa, Rita; Pamudji, Jessie Sofia
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1334

Abstract

SNEDDS is a drug delivery system that aims to increase the solubility and bioavailability of drugs that are poorly soluble in water. Increased bioavailability can improve the kinetic profile of drugs in the body. This article review aims to discuss the advantages of SNEDDS formulation used to make drugs with natural ingredient extracts. The research method applied in this article is a literature review by collecting articles in the form of journals about the formulation of SNEDDS herbal medicine. SNEDDS combines various types of oils, surfactants, and cosurfactants. The selection of SNEDDS formulation composition should be done very carefully. Research and development of SNEDDS has shown the potential of SNEDDS in increasing the solubility and bioavailability of drugs that are poorly soluble in water. Although there are many challenges to be faced in SNEDDS, SNEDDS has great potential to improve the efficiency of drug therapy.
Artikel Review: Kandungan Senyawa Aktif Tanaman Untuk Kesehatan Kulit Gunarti, Neni; Yuniarsih, Nia; Toni. S, Rifqi Maulana; Khoerunnisa, Rita; Allahuddin, Allahuddin; Anggraeni, Fera; Ruhdiana, Tita
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (435.114 KB) | DOI: 10.35617/jfionline.v14i2.86

Abstract

Abstract: Background: Skin is the outermost organ of the body that coats the human body that needs to be treated to prevent skin damage from free radicals or infection. The way to maintain and care for the skin is using synthetic compounds that can help maintain healthy skin. Another alternative in skin care is to use plants that have active compounds that are beneficial for skin health and have relatively low side effects compared to synthetic chemicals. Objective: This study aimed to determine the active compounds of plants that can improve skin health. Method: Article review using Google Schoolar database with keywords related to the research topic, namely "Active Compounds, Plants, Health, Skin". Journals used in the last 10 years (2012-2022). Results: The results of a literature review show that there are 10 plants that can improve skin health, namely yam (Pachyrhizus erosus), liquorice (Glycyrrhiza glabra), arceola cherry (Malpighia emarginata), aloe vera (Aloe vera), guava (Psidium guajava L.), tomato (Solanum lycopersicum L.), Moringa leaf (Moringa oleifera), papaya (Carica papaya L), avocado (Persea americana M.) and sweet orange (Citrus x aurantium L) The active compounds in these plants that are beneficial for skin health are alkaloids, terpenoids, phenolics, flavonoids, carotenoids, polyphenols, tannins, steroids, triterpenoids, vitamin-C, vitamin-B, niacinamide, lycopene, glabridin, saponins and antraquinones. Conclusion: Active plant compounds that are beneficial for skin health are alkaloids, terpenoids, phenolics, flavonoids, carotenoids, polyphenols, tannins, steroids, triterpenoids, vitamin-C, vitamin-B, niacinamide, lycopene,  glabridin, saponins and antraquinones.
Co-Authors Allahuddin, Allahuddin Anggraeni, Fera Gunarti, Neni Nia Yuniarsih, Nia Pamudji, Jessie Sofia Ruhdiana, Tita Toni. S, Rifqi Maulana