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All Journal Strada Journal of Pharmacy
Rizka Dianti Wahyudi
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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FORMULATION AND EVALUATION OF METAMIZOLE Na TABLETS WITH DIFFERENT CONCENTRATIONS OF SWEET POTATO FLOUR (Ipomea Batatas L.) AS DISINTEGRATOR Rizka Dianti Wahyudi; arif wijayanto
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.136

Abstract

Sweet potatoes have a fairly high starch content, namely 84.89%. High levels of starch can be used as a disintegrating agent in the manufacture of pharmaceutical preparations, namely tablets. The aim of this research is to determine the effect of variations in the concentration of sweet potato flour as a disintegrating agent and to determine how sweet potato flour is a candidate disintegrating agent in making tablet preparations using experimental methods in several concentrations on the properties and physical properties of Metamizole Na® tablets. Based on the results of this research, 3 formulations were made, namely formulation I (2.5%), formulation II (5%), formulation III (7.5%). The results obtained from this research indicate that formulation I is the best formulation of the other 3 formulas because formulation I is the formulation whose results in each test are closest to the positive control.
Co-Authors Arif Wijayanto