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Prevalence of Motor Impairments in Children with Acute Lymphoblastic Leukemia during Chemotherapy: A Systematic Review Desti Elza Muslimah; Mega Hasanul Huda; Allenidekania Allenidekania; Ayu Widya Lestari
Nursing Information Journal Vol. 5 No. 2 (2026): Nursing Information Journal
Publisher : Pusat Penelitian dan Pengabdian Masyarakat STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/nij.v5i2.1366

Abstract

Motor impairments are a frequent and disabling consequence of vincristine‑based chemotherapy in children with acute lymphoblastic leukemia (ALL). These deficits can compromise daily functioning and long‑term quality of life. This systematic review aimed to synthesize evidence on the prevalence and characteristics of motor impairments among pediatric ALL patients undergoing chemotherapy.  A comprehensive search was conducted across PubMed, ScienceDirect, Scopus, ClinicalKey, and ClinicalKey Nursing, supplemented by citation tracking. Observational studies published up to May 2025 were screened using the PEOS framework. Ten eligible studies involving 580 children were included. Outcomes assessed encompassed fine motor precision, manual dexterity, coordination, balance, agility, and strength. Motor impairments were consistently reported across all studies, with prevalence varying by treatment phase and country. During induction, prevalence ranged from 48% (USA) to 62.5% (Netherlands). In consolidation, rates reached 75.5% (Colombia). The highest prevalence was observed in the maintenance phase, with Turkey reporting 83.9% overall impairment and specific deficits in fine motor integration (70.6%), strength (74.4%), and upper‑limb coordination (61.1%). Finland showed the lowest overall prevalence (31.8%). Motor impairments are common and persistent in children with ALL receiving vincristine‑based chemotherapy, particularly during the maintenance phase. These findings underscore the need for standardized monitoring protocols, early detection, and timely rehabilitation strategies to mitigate long‑term functional decline and optimize quality of life in pediatric oncology care.
The Use of Virtual Reality to Improve Nutritional Fulfillment in Hospitalized Children: A Systematic Review Yelly Sari Arifin; Dessie Wanda; Ayu Widya Lestari; Etty Rekawati
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6211

Abstract

Hospitalized children often experience decreased appetite, which is influenced by stress and anxiety. This decrease in appetite can worsen the recovery process and increase the risk of complications. VR technology has emerged as one of the promising innovations to reduce anxiety and improve nutritional fulfillment in children during medical treatment. Objective: To evaluate the effectiveness of Virtual Reality (VR) in improving nutritional fulfillment in hospitalized children. Method: A literature search was conducted on four major databases: PubMed, ProQuest, ScienceDirect, and Scopus. Three articles with Randomized Controlled Trial (RCT) design that met the inclusion criteria were selected and analyzed in this review. The articles were evaluated using the Joanna Briggs Institute (JBI) form to assess risk of bias and methodological quality. Results: This study shows that VR is more effective than animated videos in reducing anxiety, increasing appetite, and motivating children to eat nutritious food. In addition, VR also provides benefits as an interactive educational tool that appeals to children. Conclusion: VR is a promising intervention in improving nutritional fulfillment in hospitalized children. This technology not only reduces anxiety, but also has the potential to increase children's participation in the recovery process. Further research with larger samples is needed to confirm these findings and explore the applicability of VR to different age groups and diverse medical conditions.
Effectiveness of the Pediatric Early Warning Score (PEWS) in Improving Triage Accuracy among Pediatric Patients in the Emergency Department: A Systematic Review Mariam Efendi; Allenidekania Allenidekania; Mega Hasanul Huda; Ayu Widya Lestari
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2435

Abstract

Changes in children's health status in the Emergency Department (ED) often occur suddenly, progressively, and are difficult to recognize due to children's limited verbal communication and non-specific clinical manifestations. This condition triggers a high risk of triage errors (mistriage), especially in general EDs, leading to delayed treatment and increased mortality. The Pediatric Early Warning Score (PEWS) assessment system has the potential to be a structured solution to improve assessment accuracy through objective monitoring of physiological parameters. This study aims to evaluate the effectiveness of implementing PEWS in improving triage accuracy for pediatric patients in the emergency department through a systematic review. This study employed a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was conducted across the PubMed, Scopus, ScienceDirect, Cochrane Library, and ProQuest databases for articles published between 2021 and 2025. The search strategy combined Medical Subject Headings (MeSH) terms and keywords, including "Pediatric Early Warning Score" OR "PEWS" AND "pediatric triage" OR "emergency department" OR "clinical deterioration" OR "early detection" OR "hospital admission" OR "critical care" OR "pediatric emergency". Articles were selected according to predefined inclusion criteria, and their methodological quality was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tools. A total of 17 articles were included in the review. The findings demonstrated that the implementation of the Pediatric Early Warning Score (PEWS) enhances the early detection of clinical deterioration in pediatric patients and improves triage accuracy in emergency departments. Most studies reported that PEWS has good sensitivity and specificity for predicting the need for critical care admission, thereby facilitating faster and more accurate clinical decision-making. Furthermore, the use of PEWS improves communication among healthcare professionals and enhances pediatric patient safety.