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All Journal Cermin Dunia Kedokteran
Jenita Surianggo
Faculty of Medicine and Health Sciences, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia
Health Professions

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Pemilihan Obat Anti-Epilepsi (OAE) untuk Penyandang Epilepsi Wanita Usia Subur: Tinjauan Pustaka Jenita Surianggo; Budi Riyanto Wreksoatmodjo
Cermin Dunia Kedokteran Vol 52 No 1 (2025): Obstetri & Ginekologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i1.1121

Abstract

Epilepsy is the most common chronic brain disorder and can affect people of all ages. Globally, an estimated 60 million people are diagnosed with epilepsy, half of whom are women, and about a third of women with epilepsy are of childbearing age. The main therapy for epilepsy is anti-epileptic drugs to control epileptic seizures. In Indonesia, first-line anti-epileptic drugs are carbamazepine, valproic acid, phenobarbital, and phenytoin, while second-line anti-epileptic drugs are lamotrigine, levetiracetam, clobazam, and topiramate. There are many concerns when women with epilepsy start planning a pregnancy, especially regarding the effect of epilepsy drugs on pregnancy and their effects on the fetus, such as teratogenic effects, neonatal outcomes, and neurodevelopmental impacts. The choice of anti-epileptic drugs (AEDs) in women of childbearing age must be considered carefully.
Co-Authors Budi Riyanto Wreksoatmodjo