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All Journal AcTion: Aceh Nutrition Journal
Rusdi Andid
Division of Endocrinology, Departement of Pediatrics, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The association between serum ferritin levels and growth parameters in children with β-thalassemia major Heru Noviat Herdata; Veria Taufani; Eka Destiani; Rusdi Andid
AcTion: Aceh Nutrition Journal Vol 10, No 3 (2025): September
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i3.2681

Abstract

Beta-thalassemia major requires regular blood transfusions, which can result in iron overload. Excess iron disrupts bone homeostasis by inhibiting osteoblast activity and stimulating osteoclast differentiation via elevated receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) levels, thereby increasing the risk of osteoporosis. This may lead to vertebral compression, fractures, and reduced heights. This study aimed to assess the correlation between serum ferritin concentration and linear growth parameters (height and sitting height) in adolescents with beta-thalassemia major. An observational analytical study was conducted at the Thalassemia Center of Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia, from July to August 2023 using secondary data from medical records. The study included 40 participants (21 females) who received ≥10 blood transfusions. Anthropometric measurements were assessed using WHO Reference 2007. Data were analyzed using Pearson's correlation tests. Results, most participants had serum ferritin levels >2000 ng/mL (72,5%), extremely short stature (82,5%), and abnormal sitting height (57,5%). A weak but statistically significant negative correlation was observed between serum ferritin levels and height (r = -0,165; p = 0,030) and sitting height (r = -0,150; p = 0,035). In conclusion, although the correlation is weak, elevated ferritin levels may contribute to impaired linear and spinal growth in adolescents with β-thalassemia major.
Central obesity and its association with metabolic syndrome in adolescent students of Aceh Sport High School: A cross-sectional study Nurul Nadia; Herlina Dimiati; Eka Yunita Amna; Rusdi Andid; Nora Sovira; T.M. Thaib
AcTion: Aceh Nutrition Journal Vol 10, No 2 (2025): June
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i2.2485

Abstract

Obesity remains a significant nutritional issue in the pediatric population and is closely linked to metabolic disorders. According to the World Health Organization (2022), 160 million individuals aged 5–19 years are classified as obese.  This study aimed to evaluate the association between central obesity and metabolic syndrome (MetS) in sports students. This cross-sectional study was conducted at Aceh Sports High School from May to August 2024, involving 43 students selected through simple random sampling. Although the sample size was relatively small, these findings offer valuable preliminary insights. The data collected included demographics, anthropometric measurements, blood pressure, and blood tests (glucose, HDL cholesterol, and triglycerides). Central obesity was assessed using waist circumference and MS was evaluated based on the NCEP ATP III criteria. Data were analyzed descriptively, followed by the chi-square test. The majority of the participants were not at risk of MS (51,2%). However, chi-square analysis revealed a statistically significant association between waist circumference and MetS (p<0,001, OR = 3,75 95% CI = 2,072– 6,788). In conclusion, while most participants were not at risk of MetS, central obesity emerged as a strong predictor. These findings underscore the need for early screening and intervention, even in physically active adolescents.
Co-Authors Eka Destiani Eka Yunita Amna Herlina Dimiati Heru Noviat Herdata Nora Sovira Nurul Nadia T.M. Thaib Veria Taufani