Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal AcTion: Aceh Nutrition Journal
Ika Fidianingsih
Department of Histology and Biology, Faculty of Medicine Universitas Islam, Sleman, D.I.Yogyakarta
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The effect of arrowroot diet on pancreatic and kidney histomorphology of mice induced by D-Galactose Anindya Putri Aviciena; Fatya Auliya Hening I’tikafia; Muhammad Kharisma; Syaefuddin Ali Akhmad; Ika Fidianingsih
AcTion: Aceh Nutrition Journal Vol 9, No 3 (2024): September
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v9i3.1742

Abstract

Arrowroot contains antioxidants that can potentially reduce d-galactose-induced aging of the pancreas and kidneys.  This study aimed to determine the effect of arrowroot administration on the histomorphology of the pancreas and kidneys of d-galactose-induced diabetic mice. Experimental research that was conducted in 2023 using Musculus Balb/C mice was divided into four groups as follows: a healthy control group (HC), negative control (NC) with d-galactose induction and standard feed, P1 and P2 groups with d-galactose induction, and 45% and 60% arrowroot feed. Histological slides were stained with hematoxylin and eosin. Data analysis was performed under a microscope at a magnification of 40 × 10. Severe signs of aging in the pancreas (cell atrophy, cytoplasmic vacuolation, necrosis, congestion, and inflammation) were observed in the NC and P1 groups and minimal signs were observed in the P2 group compared to the HC group, The damage mean (%) of tubular, glomerular kidney and inflammation scores were 52,46 ± 1,46, 76,66 ± 9,87, 67,99 ± 2,12, and 60,93 ± 0,55 (p=0,005); 62,64 ± 11,13, 70,48 ± 13,32, 71,25 ± 8,04, and 65,53 ±14,26, (p=0,707); 8,75 ± 2,5, 27,25 ± 4,57, 8 ± 7,25, and 13,5 ± 6,19, (p=0,001), respectively. In conclusion, administration of arrowroot affects the histomorphological features of the pancreas and kidneys of mice induced by aging using D-galactose.
Co-Authors Anindya Putri Aviciena Fatya Auliya Hening I’tikafia Muhammad Kharisma Syaefuddin Ali Akhmad