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All Journal Jurnal Kesehatan Farmasi
Dewi, I Dewa Ayu Eka Purnama
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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UJIAKTIVITAS ANTIBAKTERI GRANUL EFFERVESCENT EKSTRAK ETANOL BIJI PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli Listiani, Putu Ayu Ratih; Dewi, I Dewa Ayu Eka Purnama
Jurnal Kesehatan Farmasi Vol 7 No 1 (2025): Jurnal Kesehatan Farmasi
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkpharm.v7i1.2657

Abstract

Background: Diarrheal disease in Indonesia continues to increase every year, this has resulted in the use of drugs that continues to increase. Processing of papaya seeds (Carica papaya L.) which is formulated into effervescent granules that can act as a complementary medicine that functions to inhibit the growth of Escherichia coli bacteria that causes diarrhea. Methods: The research method is to test the antibacterial extract and effervescent granule preparationsthat have been formulated with papaya seed extract in inhibiting the growth of Escherichia coli. Results: Papaya seed extract contains alkaloids, flavonoids, saponins, terpenoids and tannins which are capable of providing antibacterial activity in inhibiting the growth of Escherichia coli bacteria. Effervescent granules with concentrations of 1.5%, 2% and 2.5% had inhibition capacities of 18.5 mm, 14 mm and 19.5 mm, respectively.Conclusion: The largest inhibition zone on effervescent granules of papaya seed extract is formulation 3, replication 2.
Co-Authors Listiani, Putu Ayu Ratih