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Arum Nuryati
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Relationship Between Hematocrit Values and The Degree of Dengue Fever in Dengue Fever Patients at Panembahan Senopati Hospital, Bantul Arum Nuryati; Hieronymus Rayi Prasetya; Diana Lestari
Jurnal EduHealth Vol. 16 No. 02 (2025): Jurnal EduHealt, Edition April - June , 2025
Publisher : Sean Institute

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Abstract

Dengue Hemorrhagic Fever (DHF) is one of the major public health problems in Indonesia. The incidence of DHF in Bantul Regency in 2019 increased compared to 2018. In 2019 there were 1,424 cases of DHF Incident Rate (IR 1.5%), while in 2018 there were 182 cases of Incident Rate (IR 0.18%). An increase in hematocrit will be found very often in cases of shock because there will be an increase (hemoconcentration) due to an increase in blood cell levels or a decrease in blood plasma levels, for example in cases of DHF. The purpose of this study was to determine the relationship between hematocrit values ​​and the severity of DHF in DHF patients. Method:This study used a cross-sectional study design, using 127 inpatient data at Panembahan Senopati Bantul Regional Hospital with the criteria; having symptoms of Dengue Hemorrhagic Fever who were hospitalized by undergoing hematocrit examination using a hematology analyzer in 2022. The results of the analysis showed a relationship between hematocrit values ​​and the severity of DHF with a value of p = 0.14 and r = 0.13. Conclusion: There is no relationship between hematocrit values ​​and the severity of DHF in DHF patients.
Leukositosis pada Pasien Skizofrenia yang Mendapat Terapi Obat Antipsikotik : Leukocytosis in Schizophrenia Patients Receiving Antipsychotic Drug Therapy Hieronymus Rayi Prasetya; Arum Nuryati; Sri Murtiningrum; Rizky Windi Ramadhani
Jurnal Kolaboratif Sains Vol. 7 No. 2: FEBRUARI 2024
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.852 KB) | DOI: 10.56338/jks.v2i1.667

Abstract

Latar Belakang : Skizofrenia adalah gangguan pikiran yang disebabkan hiperaktivitas dopaminergik yang ditandai dengan ketidakmampuan berpikir, emosi dan tingkah laku. Tata laksana pengobatan skizofrenia ialah pemberian obat antipsikotik salah satunya Clozapine. Clozapine mampu bekerja dengan menyeimbangkan zat alami kimia otak dengan cara memblokir reseptor dopamin, histamin, dan serotonin Namun, Clozapine juga memiliki efek samping diantaranya dapat terjadinya leukopenia ataupun leukositosis. Tujuan penelitian ini untuk mengetahui jumlah leukosit pada pasien skizofrenia yang mendapat terapi obat antipsikotik di RSJ Prof. Dr. Soerojo Magelang. Metode : Penelitian ini menggunakan metode deskriptif kualitatif, bertujuan untuk mengetahui gambaran jumlah leukosit pada pasien skizofrenia yang mendapat terapi obat antipsikotik. Sampel pada penelitian ini adalah seluruh pasien dengan diagnosis skizofrenia yang dirawat di RSJ Prof. Dr. Soerojo Magelang pada bulan Januari – Desember 2022 sejumlah 398 pasien. Hasil : Dari hasil analisa pasien yang mengalami leukopenia berdasarkan kombinasi obat yaitu pada kombinasi 2 obat (0,25%) dan kombinasi 3 obat terdapat (0,25%). Pasien yang mempunyai jumlah leukosit normal pada obat tunggal (0,50%), kombinasi 2 obat (2,26%), kombinasi 3 obat (7,80%), kombinasi 4 obat (30,40%), kombinasi 5 obat (33,92%), dan kombinasi 6 obat (1,01%). Pasien yang mengalami leukositosis pada obat tunggal (0,25%), kombinasi 2 obat (0,25%), kombinasi 3 obat (4,02%), kombinasi 4 obat (8,04%), kombinasi 5 obat (10,55%) dan kombinasi 6 obat (0,50%). Kesimpulan : Pasien yang mengalami leukopenia berjumlah 2 orang (0,50%) dengan rata-rata 3.400 sel/µl, pasien dengan jumlah leukosit normal berjumlah 302 orang (75,5%) dengan rata-rata 8.558 sel/µl dan pasien yang mengalami leukositosis berjumlah 94 orang (24%) dengan rata-rata 13.328 sel/µl.
Treatment Outcome of Pulmonary Tuberculosis Patients in Public Health Center Arisandi, Desto; Nurlaili Farida Muhajir; Arum Nuryati
JURNAL KESEHATAN PRIMER Vol 10 No 2 (2025): JKP (Jurnal Kesehatan Primer)
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/jkp.v10i2.2258

Abstract

Background: Tuberculosis (TB) remains a contagious disease with high mortality rates worldwide, especially in developing countries like Indonesia, which is the second-largest contributor to TB cases after India. Objective: Analysis of factors associated with treatment outcome in pulmonary TB patients in public health centers at Gunungkidul Regency, D.I. Yogyakarta. Methods: An observational analytic study with a cross-sectional design was conducted on pulmonary TB patients in 30 public health centers, Gunungkidul Regency in 2020-2021. Inclusion criteria were age ≥15 years, and exclusion criteria were extrapulmonary TB patients and those who loss to follow-up the end of treatment. Secondary data were obtained from the Tuberculosis Information System TB 03 (SITB) of the Gunungkidul District Health Office. The research data were analyzed using chi-square test (bivariate) and logistic regression (multivariate). Results: A total of 272 pulmonary TB patients in 2020-2021, with the majority aged 45-54 years (22.8%), male (57%), new treatment category (96.3%), BTA/TCM positive (58.1%), had a history of DM (8.1%), and HIV positive status (0.8%). Logistic regression analysis showed that age (p<0.001) and bacteriological examination results (p=0.012) were significantly associated with treatment outcomes. However, gender, history of TB treatment, history of DM, and HIV status were not associated with treatment success. Conclusion: Age and bacteriological examination results (AFB/Xpert MTB) at the start of treatment contributed to the treatment success rate in pulmonary TB patients.
Co-Authors Desto Arisandi Diana Lestari Hieronymus Rayi Prasetya Nurlaili Farida Muhajir Rizky Windi Ramadhani Sri Murtiningrum