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All Journal Indonesian Journal of Tropical and Infectious Disease Buletin Kedokteran dan Kesehatan Prima
Jimanto, Vincent
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Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Medicine & Pharmacology Nursing Public Health

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Rare manifestation of orbital hematoma in hemophilia B: A case report Jimanto, Vincent; Ritonga, Dwi Herawati
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6621

Abstract

Introduction: Severe Hemophilia B is a blood coagulation disorder with the most common clinical manifestation is bleeding manifestation in major joint. In this article, we present a case of 5-year-old boy with severe hemophilia B, whose clinical bleeding manifestation was rarely reported, located in unilateral orbital hematoma. By reporting this case of hemophilia B with rare clinical manifestations, we aim to increase the awareness so as to accelerate the diagnosis and management of hemophilia B. Case Presentation: A 5-year-old boy came to the emergency ward with complaints of a swollen and bluish right eye socket since a week prior to admission. Patient also experienced other symptoms such as frequent joint pain, prolonged bleeding after injury, and bruises (hematoma) on the trunk, elbows, and knees. The coagulation tests showed a prolonged APTT with normal PT and INR. Due to resource-limited setting, sample referral was needed to perform factor VIII and IX examination, and FFP transfusion was given to the patients during the admission. Factor VIII and IX results were available after patient had been discharged, with a low-level activity of factor IX (<1%). Patient was diagnosed as severe hemophilia B, and was referred to tertiary health-care facility from outpatient department for comprehensive management. Conclusion: Despite of the most common location of bleeding manifestation in Hemophilia B, other bleeding manifestation such as orbital hematoma should also be considered as Hemophilia B manifestation. Early diagnosis and prompt treatment will give a better prognosis for patient with hemophilia.
Current Profile of Vivax Malaria in Isolated Area of Kualuh Leidong Pasaribu, Ayodhia Pitaloka; Jimanto, Vincent; Ainur, Framita
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.58715

Abstract

The Indonesian Ministry of Health targets to eliminate malaria by 2030. Vivax malaria, a challenging variant to eradicate, is prevalent in areas near elimination, including North Sumatra, which ranks fourth in malaria cases in Indonesia. Labura district, a part of North Sumatra, had a low-endemic status until 2020. However, an increase in cases occurred in 2021 within the Kualuh Leidong subdistrict, the primary contributor to Labura's malaria cases. This shifted the endemicity status from low to moderate. The objective of the study is to assess the malaria case profile in this region. A descriptive approach was used, employing a total sampling method at Tanjung Leidong Health Center between September 2022 and July 2023. This observational study identified 494 vivax malaria cases. Predominantly affecting males (60.9%), cases peaked in adults (>18 years) with 314 cases (63.6%). Microscopic examination was the leading diagnostic tool, used in 463 cases (93.7%). The health center primarily administered national regimen therapies dihydroartemisinin-piperaquine (DHP) + primaquine in 204 cases (62.4%), whereas others received alternate therapies. All patients recovered without referrals. Over 11 months, seven recurrence cases emerged, with five receiving quinine+primaquine. Vivax malaria cases in Kualuh Leidong have seen a significant increase compared to previous years. The attention and collaboration of all parties, both from the health center and the community, are necessary to achieve malaria elimination by 2030.
Rare manifestation of orbital hematoma in hemophilia B: A case report Jimanto, Vincent; Ritonga, Dwi Herawati
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6621

Abstract

Introduction: Severe Hemophilia B is a blood coagulation disorder with the most common clinical manifestation is bleeding manifestation in major joint. In this article, we present a case of 5-year-old boy with severe hemophilia B, whose clinical bleeding manifestation was rarely reported, located in unilateral orbital hematoma. By reporting this case of hemophilia B with rare clinical manifestations, we aim to increase the awareness so as to accelerate the diagnosis and management of hemophilia B. Case Presentation: A 5-year-old boy came to the emergency ward with complaints of a swollen and bluish right eye socket since a week prior to admission. Patient also experienced other symptoms such as frequent joint pain, prolonged bleeding after injury, and bruises (hematoma) on the trunk, elbows, and knees. The coagulation tests showed a prolonged APTT with normal PT and INR. Due to resource-limited setting, sample referral was needed to perform factor VIII and IX examination, and FFP transfusion was given to the patients during the admission. Factor VIII and IX results were available after patient had been discharged, with a low-level activity of factor IX (<1%). Patient was diagnosed as severe hemophilia B, and was referred to tertiary health-care facility from outpatient department for comprehensive management. Conclusion: Despite of the most common location of bleeding manifestation in Hemophilia B, other bleeding manifestation such as orbital hematoma should also be considered as Hemophilia B manifestation. Early diagnosis and prompt treatment will give a better prognosis for patient with hemophilia.
Co-Authors Ainur, Framita Pasaribu, Ayodhia Pitaloka Ritonga, Dwi Herawati