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All Journal Jurnal IPTEK Bagi Masyarakat JURNAL REKAYASA KIMIA & LINGKUNGAN
Marbun, Sarah Aknesia
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Agriculture, Biological Sciences & Forestry Humanities Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Energy Engineering Mechanical Engineering Physics Public Health Social Sciences

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Synthesis of Microgel Sulfated Carboxymethyl Cellulose (SCMC) by Double Crosslinked Alginate from Lindur Fruit (Bruguiera gymnorrhiza) for Diabetic Ulcer Healing Hutapea, Jobin Armando; Zaki, Nesfitra Dzakwan; Syahrum, Silvina Faradilla; Putra, Surya Andika; Marbun, Sarah Aknesia; Tarigan, Indra Lasmana
Jurnal Rekayasa Kimia & Lingkungan Vol 20, No 1 (2025): Jurnal Rekayasa Kimia & Lingkungan (June, 2025)
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23955/rkl.v20i1.40112

Abstract

Microgels have been recognized as promising scaffolds for diabetic wound care due to their favorable properties in promoting wound healing. This study aims to synthesize a microgel using sulfated carboxymethyl cellulose (SCMC) derived from Lindur fruit (Bruguiera gymnorrhiza) for potential application in diabetic ulcer treatment. The synthesis was conducted through a double-crosslinking reaction, and the resulting microgel was characterized using infrared (IR) spectroscopy, scanning electron microscopy (SEM), and in vivo analysis in male mice (Mus musculus). The results demonstrated that the yield of Ca-alginate isolate ranged from 18.67% to 19.46%, with a purity of 19.5%33.1%, viscosity of 31.1931.46 cP, and stable pH at 7. The Ca-alginate isolate exhibited antioxidant activity at 50 ppm with an inhibition percentage of 22.3%. The modification of SCMC was successfully achieved, as confirmed by the presence of characteristic absorption peaks at 1220 cm (asymmetric SO stretching) and 870 cm (symmetric COS stretching vibrations), indicating successful sulfate group incorporation. The microgel swelling ratio was recorded at 660% for microgel A, 700% for microgel B, and 720% for microgel C, with microgel C exhibiting the highest swelling capacity. In vivo wound healing assessment revealed that microgel C facilitated more rapid wound closure, with wound sizes reducing progressively from 0.9 cm on day 3 to 0.5 cm on day 5, 0.3 cm on day 7, and 0.1 cm on day 14. These findings suggest that SCMC-based microgel with alginate derived from Lindur fruit holds significant potential as an innovative formulation for diabetic wound management
Pendampingan Ibu PKK Mengolah Kulit Pisang Menjadi Cookies Untuk Mendukung Pencegahan Stunting Fadhil, Ahmad; Rahmasari, Nadia; Tambunan, Betharia Juli Mas; Marbun, Sarah Aknesia; Rahayu, Rosi; Latief, Madyawati; Tarigan, Indra Lasmana
Jurnal IPTEK Bagi Masyarakat Vol 5 No 1 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v5i1.1267

Abstract

Indonesia is one of the largest banana-producing countries, yet banana peels, which are rich in nutrients, are often discarded as waste. On the other hand, stunting remains a significant health problem, especially in the Jambi region. This community service activity aims to empower PKK women in Simpang Limo Village to process banana peels into healthy cookies as an alternative effort to support stunting prevention. The program was carried out for three months (August–November 2024) involving thirty participants. The methods used included observation, socialization, training on making banana peel flour, and practice in making banana peel-based cookies. The post-training survey results showed a moderate level of knowledge but high interest, with 36.9% of respondents expressing willingness to produce banana peel cookies and 15.4% considering this innovation a positive step in waste reduction. The cookies produced received positive responses, with the community noting their good taste, crunchy texture, and distinctive aroma. This activity shows that the utilization of banana peels has the potential to produce nutritious and economically valuable food products, while also improving the skills of PKK women and potential supporting efforts to reduce stunting.
Co-Authors Ahmad Fadhil, Ahmad Hutapea, Jobin Armando Indra Lasmana Tarigan Madyawati Latief Putra, Surya Andika Rahayu, Rosi Rahmasari, Nadia Syahrum, Silvina Faradilla Tambunan, Betharia Juli Mas Zaki, Nesfitra Dzakwan