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p-Index From 2021 - 2026
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All Journal Global South Review Journal Of World Science
Wu, Wenbo
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Humanities Computer Science & IT Economics, Econometrics & Finance Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences Other

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The Efficacy of Liposomal Bupivacaine in Managing Postoperative Pain, a Systematic Review and Meta-Analysis of Randomized Control Trials Da Silva, Helena Soares; Gong, Hualei; Wu, Wenbo; Fang, Zhenning; Mo, Kai
Journal of World Science Vol. 4 No. 3 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i3.1376

Abstract

Postoperative pain, a significant surgical complication, presents a considerable challenge to the healthcare system, resulting in adverse outcomes, disability, prolonged hospitalization, and financial strain. This study seeks to evaluate the effectiveness of liposomal bupivacaine (LB) in postoperative pain management by a systematic review and meta-analysis of existing research. PubMed, CENTRAL, Embase, Web of Science, and Google Scholar were searched for randomized controlled trials (RCTs) published until January 2025, focusing on adults (18 years) undergoing surgical procedures where LB was administered via wound infiltration, nerve blocks, or periarticular injections. Primary outcomes included pain scores (VAS/NRS/BPI), opioid consumption, adverse events (e.g., nausea/vomiting), and patient satisfaction. A total of 763 papers were discovered in the literature, of which 21 (Barrington et al., 2017) were included. The pooled standardized mean difference (SMD) was -0.53, (95% CI, [-0.84, -0.23]; p = 0.0006) signifying a statistically significant decrease in pain levels favoring the intervention group. No significant disparity in opioid use was found between the two groups. The combined odds ratio (OR) was 0.78 (95% confidence interval (CI): [0.46 to 1.31]; [p = 0.35), indicating no significant difference in the incidence of nausea and vomiting. LB is effective in alleviating pain, diminishing opiate usage, and alleviating postoperative side effects.
Three Concepts of Internationalism in the Global South: Solidarism, Pluralism, and Developmentalism Wu, Wenbo
Global South Review Vol 5, No 2 (2023): Global South Review
Publisher : Institute of International Studies

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/globalsouth.92057

Abstract

Throughout modern history, internationalism has been one of the most powerful forces that drives global political changes. While existing research focuses exceptionally on liberal internationalism, studies devoted to internationalism beyond its liberal and Western forms remain relatively scant. Building on a conception that perceives internationalism as a form of human practices, this article explores the evolution of the concept of internationalism in the Global South through a series of political practices from the drafting of the Universal Declaration of Human Rights in 1948 and the 1955 Asian-African Conference in Bandung to the proposal of the New International Economic Order in 1974 and the BRICS’s contestation over NATO’s Libyan intervention in 2011. It is argued that the normative core of internationalism in the Global South is constituted of three major components – pluralism, solidarism, and developmentalism, each in its particular form. Taken together, it envisions an international order rooted in the solidarity of the post-colonial peoples based on their shared colonial past, underpinned by a pluralistic outlook of political life, and places emphasis on redistributive justice in structuring the international economic order. Though some argue that with the rise of the BRICS countries, there will be a revival of Global South internationalism, this article concludes that this is not likely to happen at present.
Co-Authors Da Silva, Helena Soares Fang, Zhenning Gong, Hualei Mo, Kai