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Al-Shammari, Mohammed J.I.
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Alterations in Selected Blood Parameters Associated with Type 2 Diabetes Mellitus: Perubahan Parameter Darah Tertentu yang Berhubungan dengan Diabetes Melitus Tipe 2 Al-Shammari, Mohammed J.I.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

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Abstract

Background: Non-insulin-dependent diabetes mellitus (NIDDM), also known as type 2 diabetes, is associated with various physiological and biochemical changes in the blood. Understanding these changes is important for better disease management and prevention of complications. Aims of the Study: This study aimed to investigate certain physiological and biochemical changes in blood parameters among patients with non-insulin-dependent diabetes mellitus (NIDDM) and compare the results with a healthy control group. Methodology: The study included a total of 50 participants (men and women) aged between 20 and 70 years. They were divided into two groups: 30 diabetic patients (18 females and 12 males) and 20 healthy individuals (11 males and 9 females). Blood samples were analyzed to assess various hematological and biochemical parameters. Results: The findings revealed no significant differences in red blood cell count, total leukocyte count, and the percentages of neutrophils, lymphocytes, and eosinophils between the diabetic and control groups. However, a slight, non-significant increase in platelet count was noted in diabetic patients. A significant increase (p < 0.001) was observed in both total cholesterol and triglyceride levels in the diabetic group compared to the controls. Additionally, a statistically significant difference in age was found between diabetic patients and healthy individuals (p = 0.0007), suggesting age as a potential contributing factor in the development and progression of NIDDM. Conclusions: The study highlights the significant elevation of cholesterol and triglyceride levels in individuals with NIDDM and underscores the potential role of age in the onset and progression of the disease. Regular monitoring of these parameters may aid in better management of diabetic patients.Highlight : Diabetic patients had significantly higher cholesterol, triglyceride, FBS, and HbA1c levels. No notable differences in RBC, WBC, or platelet counts were found between groups. Monitoring biochemical markers is vital for diabetes management. Keywords : Type 2 Diabetes, Blood Parameters, Cholesterol, Triglycerides, Glycemic Control
Functional Capabilities of the Cardiorespiratory System in 15-17 Years-Old Female Students: Kemampuan Fungsional Sistem Kardiorespirasi pada Siswi Berusia 15-17 Tahun Al-Shammari, Mohammed J.I.; Ismail, Masar Hadi; Noor, Zaman Atiea Sabah,; Jumaa, Hassan.; A, Pogrebnyak Tatyana; N, Khorolskaya Elena; E., 7Grigorenko Svetlana
Academia Open Vol. 10 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.12232

Abstract

Background: Physiological adaptation during adolescence is influenced by lifestyle and environmental factors, particularly in urban and rural settings. Understanding cardiorespiratory responses to physical activity is crucial for assessing health reserves in young individuals. Aim of the Study: To evaluate physical development and the functional status of the cardiorespiratory system at rest and after physical load among first-year female medical college students from urban and rural areas. Methodology: The study included female students aged 15–16. Physical development was assessed using somatometry (height, weight, chest circumference) and physiometry methods (vital lung capacity [VC], tidal volume [TV], expiratory reserve volume [ERV], heart rate [HR], and blood pressure [SBP, DBP]). Percentile methods and spirometry were applied to measure external respiration indices. Physical load was induced using G.N. Apanasenko’s squat test. Data were processed statistically using integrative indices (vital index, Erisman index). Results: After loading, HR significantly increased in both groups: from 84.6±2.3 to 130.0±4.6 in group I and from 78.1±2.1 to 134.7±3.4 in group II. SBP and DBP also rose markedly, reaching 150.0±5.0 and 162.0±3.4 mmHg, respectively. Cardiac output (CO) increased to 12.69±0.33 L/min in group I and 12.92±0.25 L/min in group II. VC, TV, and ERV remained largely unchanged, while SpO₂ dropped significantly after loading to 82.7±1.4% and 84.0±1.6% in groups I and II, respectively. Conclusion: Urban and rural students exhibited similar adaptive patterns, with rural students showing slightly better oxygen saturation and CO response, suggesting higher functional reserves and greater cardiorespiratory adaptability under physical stress.Highlight : Heart rate and blood pressure rose significantly after physical load. Oxygen saturation dropped, more stable in rural students. Rural students showed better functional reserves and adaptability Keywords : Female Students, Heart Rate, Blood Pressure, Cardiorespiratory System, Physical Activity
Co-Authors A, Pogrebnyak Tatyana E., 7Grigorenko Svetlana Ismail, Masar Hadi Jumaa, Hassan. N, Khorolskaya Elena Noor, Zaman Atiea Sabah,