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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Sehat Rakyat: Jurnal Kesehatan Masyarakat
Erna Kristiyani
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Navigating Diagnosis and Treatment of Perianal Condyloma Acuminata in a Bisexual Man: Clinical and Histopathological Insights Rose Widanti Sugiyanto; Erna Kristiyani; Ketut Kwartantaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 7 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i7.1332

Abstract

Background: Condyloma acuminata (CA), caused by Human Papillomavirus (HPV), commonly affects the anogenital region, particularly in young, sexually active individuals. Perianal presentation is less common but significant, often linked to specific sexual practices. Bisexual men represent a unique demographic concerning STI risk factors and require careful assessment. This report details the diagnosis and management of perianal CA in a young bisexual male, emphasizing the diagnostic utility of clinical assessment, sexual history, and histopathology. Case presentation: A 24-year-old Indonesian bisexual male presented with a three-month history of progressively enlarging, asymptomatic perianal nodules. He reported unprotected receptive anal intercourse with a male partner five months prior. Examination revealed multiple skin-colored, verrucous papules in the perianal region. HIV and syphilis screenings were negative. Histopathological examination of a biopsy specimen confirmed CA, showing parakeratosis, papillomatosis, acanthosis, and koilocytosis. Conclusion: Treatment with 90% trichloroacetic acid (TCA) combined with cauterization resulted in significant clinical improvement at one-week follow-up. This case highlights the importance of obtaining a thorough, non-judgmental sexual history, recognizing characteristic lesion morphology, and utilizing histopathology for definitive diagnosis in managing perianal CA, particularly in populations with diverse sexual practices.
Navigating Diagnosis and Treatment of Perianal Condyloma Acuminata in a Bisexual Man: Clinical and Histopathological Insights Rose Widanti Sugiyanto; Erna Kristiyani; Ketut Kwartantaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 7 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i7.1332

Abstract

Background: Condyloma acuminata (CA), caused by Human Papillomavirus (HPV), commonly affects the anogenital region, particularly in young, sexually active individuals. Perianal presentation is less common but significant, often linked to specific sexual practices. Bisexual men represent a unique demographic concerning STI risk factors and require careful assessment. This report details the diagnosis and management of perianal CA in a young bisexual male, emphasizing the diagnostic utility of clinical assessment, sexual history, and histopathology. Case presentation: A 24-year-old Indonesian bisexual male presented with a three-month history of progressively enlarging, asymptomatic perianal nodules. He reported unprotected receptive anal intercourse with a male partner five months prior. Examination revealed multiple skin-colored, verrucous papules in the perianal region. HIV and syphilis screenings were negative. Histopathological examination of a biopsy specimen confirmed CA, showing parakeratosis, papillomatosis, acanthosis, and koilocytosis. Conclusion: Treatment with 90% trichloroacetic acid (TCA) combined with cauterization resulted in significant clinical improvement at one-week follow-up. This case highlights the importance of obtaining a thorough, non-judgmental sexual history, recognizing characteristic lesion morphology, and utilizing histopathology for definitive diagnosis in managing perianal CA, particularly in populations with diverse sexual practices.
Kepatuhan Pengobatan Multi-Drug Therapy (MDT) dan Faktor yang Mempengaruhinya pada Pasien Morbus Hansen di RSUD RAA Soewondo Pati Elly Mazida; Erna Kristiyani; Shirly Gunawan
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.5938

Abstract

Hansen’s disease (leprosy) remains a public health problem in Indonesia. Although national elimination was declared in the year 2000, the number of new cases has remained stagnant at around 17,000–20,000 cases per year, and the proportion of Grade 2 Disability (G2D) remains high. Social stigma, delayed diagnosis, and poor adherence to Multi-Drug Therapy (MDT) continue to be major challenges in achieving elimination. This study aims to evaluate MDT adherence based on three Hansen’s disease patients and to analyze the factors influencing it. This research uses a descriptive design with a three-case report approach analyzed from a public health perspective. The variables assessed include MDT adherence, family support, stigma, patient knowledge, and drug adverse effects. Two of the three patients demonstrated high adherence to MDT, while one patient exhibited non-adherence due to a severe drug reaction (dapsone hypersensitivity syndrome). Factors influencing adherence include patient knowledge, drug side effects, family support, and special conditions such as pregnancy. MDT adherence remains a challenge in leprosy elimination efforts. A multidisciplinary approach involving education, intensive monitoring, and stigma prevention is needed to improve treatment success.
Co-Authors Elly Mazida Ketut Kwartantaya Rose Widanti Sugiyanto Shirly Gunawan