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Kajian Fitokimia dan Analisis Kadar Fenolik Total Ekstrak Metanol Kulit Batang Merawan (Hopea mengarawan Miq.) Pratibha, Muhammad Govindo Ibra; Rahmadanti, Diah Vio; Elviana, Dina; Ramadhan, Muhammad Farras; Pratama, Ngakan Putu Agung Dharma; Pramudia , Rista Anggi; Noviany, Noviany
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.580

Abstract

Dipterocarpaceae is a family of plants that has good wood quality and durability. Apart from that, wood for this family is known to contain the compound resveratrol which has bioactivity, such as anti-cancer and anti-inflammatory. Several genus and species of this family are threatened with extinction. Merawan (Hopea mengarawan Miq.) is one of  extinct species from Dipterocarpaceae which according to several research contains secondary metabolite compounds. The objective of this research was to determine the content of secondary metabolite compounds and determine the total phenolic content of merawan. The maceration method was used to extract the stem bark of H. mengarawan Miq., then continued with phitochemical screening, and total phenolic content analysis. Phytochemical screening was carried out to identify secondary metabolite compounds contained in the methanol extract of H. mengarawan Miq. stem bark qualittatively. Determination of total phenolic content was carried out using the colorimetric method with Folin-Ciocalteu reagent and gallic acid as a comparison standard. The result of this study indicate that the methanol extract of stem bark of  H. mengarawan Miq. contains secondary metabolite compounds, such as saponins, steroids, tannins, alkaloids, flavonoids, and phenolic with the total phenolic content of 13,518±0,228 mg GAE/g.
SEVERE TOXOCARA CATI INFECTION IN A DOMESTIC CAT: A CASE STUDY WITH PATHOLOGICAL AND HISTOPATHOLOGICAL FINDINGS IN SAYAN VILLAGE, UBUD Elviana, Dina; Suratma, Nyoman Adi; Berata, I Ketut; Suarjana, I Gusti Ketut; Suardana, Ida Bagus Kade
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2026 Vol. 18 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2026.v18.i01.p28

Abstract

Toxocariasis is a disease caused by worms of the genus Toxocara. In chronic cases, toxocariasis can lead to mortality due to damage to vital organs, including the lungs, liver, and intestines. The objective of this case study is a 2-month-old cat from Sayan Village, Ubud Subdistrict, Gianyar Regency, Bali, Indonesia. This case study aims to establish a diagnosis based on anamnesis, clinical signs, epidemiological data, anatomical pathology, histopathology, and laboratory examination results. Clinical symptoms observed in the case cat included emaciation, an enlarged abdomen, eye discharge, pale gums, rough fur, and liquid, foamy feces. Anatomical pathology examination revealed the presence of Toxocara cati worms, with a total count of 43 worms distributed throughout the small intestine, stomach, esophagus, trachea, and lungs. Fecal examination using qualitative methods detected Toxocara cati worm eggs. Histopathological observations indicated eosinophilic inflammatory cell infiltration in the small intestine and trachea. It was concluded that the case cat was diagnosed with toxocariasis. It was concluded that the cat was diagnosed with toxocariasis, which contributed to the severity of clinical symptoms and potentially mortality, emphasizing the need for effective preventive and biosecurity measures.