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Febriani , Yessi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Uji Efektivitas Flavonoid Total Ekstrak Etanol Kulit Batang Nangka (Artocarpus heterophyllus Lam) Terhadap Penyembuhan Luka Sayat Pada Ayam Broiler (Gallus domesticus) Kemalasari , Nurisma; Sumardi, Sumardi; Febriani , Yessi
Journal of Pharmaceutical and Sciences JPS Volume 1 Nomor 1 (2018)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v1i1.1

Abstract

Jackfruit (Artocarpus heterophyllus Lam) is a local plant found in various regions in Indonesia. This jackfruit tree is usually used as traditional medicine. This study aims to examine the ethanol extract of jackfruit bark against wound healing on broiler skin and determination of total flavonoid content using the calorimetry method. This study began with identification of plants, taking jackfruit bark, processing of jackfruit bark simplicia, making ethanol extract of jackfruit bark (Artocarpus heterophyllus Lam), measuring the total flavonoid content of ethanol extract of jackfruit bark, preparation of test animals, wound cutting on chicken skin, effectiveness test of total flavonoid ethanol extract of jackfruit bark (Artocarpus heterophyllus Lam) on wound healing in broiler chickens (Gallus domesticus), data analysis. The results showed that the administration of ethanol extract of jackfruit bark (Artocarpus heterophyllus Lam) to wound healing on the skin of broiler chickens (Gallus domesticus) had a better healing effect than negative controls. The results of applying 4 times in 24 hours provide the fastest healing effect on cuts on the skin of broiler chickens (Gallus domesticus). Based on statistical results there are 86.1% of flavonoids that affect the area of the curve and affect the healing of the area of incisions in chickens.
Formulasi sabun mandi esensial minyak nilam dengan pewarna kopigmentasi biji kesumba keling (Bixa orellana L.) dengan angkak merah Indriana , Meutia; Sari, Nurmala; Julianty , Siti Muliani; Muzakkir, Muzakkir; Febriani , Yessi; Nurrahman, Taufik; Salman, Salman
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.342

Abstract

Background; The skin is the outermost layer of the body that serves as a protective barrier against exposure to sunlight and is also where sweat is produced. Sweat can make the skin appear dull and sticky. Soap is a cosmetic product that is used for body cleansing. Annatto and red mold rice are used as natural colorants formulated in soap preparations, where the color produced by annatto and red mold rice is not stable. Therefore, a copigmentation method is needed to stabilize the colorant annatto with red mold rice. Method; This research use an experimental approach that initially involves the extraction of annatto seeds and red mold rice using 96% ethanol. Subsequently, the extracted compounds are formulated into soap preparations with variations in ratios of 1:1, 1:2, 2:1, and 2:2. To evaluate the quality of the soap preparations, various tests have been conducted, including homogeneity testing, pH testing, foam height testing, water content testing, and irritation testing. Result; The results showed that the copigmentation of annatto seeds with red mold rice in the form of ethanol extract could be formulated into a soap dosage form at a ratio of 2:1 (F4) is the best preparation, is a homogeneous preparation, has a pH of 9.4 , has a foam height of 8.3 cm, has a water content of 6.25%. All copigmented soap with ethanol extract of annatto seeds with red mold rice does not irritate the skin of the hands.
Formulasi dan Evaluasi Gel Pengharum Serai Wangi dengan Kombinasi Basis Karagenan, Xanthan Gum, dan HPMC Anggraini, Windi; Salman, Salman; Febriani , Yessi; Indriana , Meutia; Muzakkir, Muzakkir
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1459

Abstract

Background: Unpleasant odors in bathroom areas are a common hygiene problem that requires practical and environmentally friendly solutions. Citronella oil (Cymbopogon nardus L. Randle) is known to contain active compounds with a distinctive aroma that has potential as a natural fragrance agent. However, an appropriate gel base is needed to maintain the stability and aroma retention of the preparation. Objective: This study aims to formulate and evaluate a bathroom fragrance gel from citronella oil with a combination of carrageenan, xanthan gum, and hydroxypropyl methylcellulose (HPMC) bases and to determine the concentration of citronella oil that produces the preparation with the best physical stability and aroma retention. Methods: This research was an experimental laboratory study. Citronella oil was formulated into gel preparations with four concentration variations (2.5%; 5%; 7.5%; and 10%) using a combination of carrageenan, xanthan gum, and HPMC bases. Evaluation of the preparations included organoleptic test, syneresis, liquid evaporation, preference test (hedonic), and aroma retention test for 15 days of storage. Data were analyzed statistically with a 95% confidence level. Results: The results showed that all formulas produced gels with good organoleptic characteristics (cloudy white color, characteristic citronella aroma, and semi-solid texture). The formula with 10% citronella oil concentration (F4) showed the best results with the lowest syneresis value (0.62%), the lowest liquid evaporation percentage (21.69%), and the highest remaining gel weight (92.03%). The preference test showed that F4 had the highest average value (4.25) in the like category, and the best aroma retention with a score range of 4.19-4.70 until day 15. Conclusion: The combination of carrageenan, xanthan gum, and HPMC bases can produce physically stable bathroom fragrance gel preparations. The formula with 10% citronella oil concentration (F4) is the best formulation and has the most potential to be developed as a natural bathroom fragrance product.
Co-Authors Anggraini, Windi Indriana , Meutia Julianty , Siti Muliani Kemalasari , Nurisma Muzakkir Muzakkir Nurmala Sari Nurrahman, Taufik Salman Salman Sumardi .