The development of the business world and the increasing business competition that is increasingly competitive, along with the rapid economic growth and technological advances in the era of globalization, requires various changes, especially in strategy formulation. MSME players must make several changes in marketing strategies due to the rapid development of technology. MSMEs play an important role in the national economy, but still face obstacles in utilizing modern technology such as e-commerce and ERP, which should be able to increase their efficiency and competitiveness. The use of e-commerce and enterpirse resource planning (ERP) can help MSMEs to compete with other MSMEs. This study aims to determine the effect of the use of e-commerce and enterprise resource planning on the level of profit at UMKM Pottery Craftsmen in Kasongan Village, Bantul, Yogyakarta Special Region. This research uses a quantitative approach with questionnaires as the main instrument for collecting data. The sample was determined using purposive sampling method. The sample that met the research criteria was 275. However, to determine the minimum number of respondents used using the Slovin formula, which resulted in 75 as the minimum sample size. Researchers determined the number of respondents as many as 80 people in order to increase the validity and representativeness of the data in this study. The results of the research that have been conducted show that e-commerce and enterprise resource planning have a positive and significant effect on the profit level of MSMEs of pottery craftsmen in Kasongan Village, Yogyakarta Special Region. E-commerce and ERP affect the profit level of MSMEs through operational efficiency and expansion of market access. This emphasizes the need for technological support and training for MSMEs in order to optimize the benefits of digitalization in their business.Keywords: MSME, E - commerce, ERP, Profit level.