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Optimizing diabetes prediction using machine learning: a random forest approach Maenge, Aone; Sigwele, Tshiamo; Bhende, Cliford; Mokgethi, Chandapiwa; Kuthadi, Venumadhav; Omogbehin, Blessing
International Journal of Advances in Applied Sciences Vol 14, No 2: June 2025
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijaas.v14.i2.pp454-468

Abstract

Diabetes, a leading cause of global mortality, is responsible for millions of deaths annually due to complications such as heart disease, kidney failure, and stroke. Projections indicate that 700 million people will be affected by diabetes in 2045, placing immense strain on global healthcare systems. Early detection and accurate prediction of diabetes are essential in mitigating complications and reducing mortality rates. However, existing diabetes prediction frameworks face challenges, including imbalanced datasets, overfitting, inadequate feature selection, insufficient hyperparameter tuning, and lack of comprehensive evaluation metrics. To address these challenges, the proposed random forest diabetes prediction (Random DIP) framework integrates advanced techniques such as hyperparameter tuning, balanced training, and optimized feature selection using a random search cross-validation (RandomizedSearchCV). This framework significantly improves predictive accuracy and ensures reliable clinical applicability. Random DIP achieves 99.4% accuracy, outperforming related works by 7.23%, the area under curve (AUC) of 99.6%, surpassing comparable frameworks by 7.32%, a recall of 100%, exceeding existing models by 9.65%, a precision (97.8%), F1-score (98.9%), and outperformance of 6.69%. These metrics demonstrate Random DIP's excellent capacity to identify diabetes cases while minimizing false negatives (FPs) and providing reliable predictions for clinical use. Future work will focus on integrating real-time clinical data and expanding the framework to accommodate multi-disease prediction for broader healthcare applications.
A review on ischemic heart disease prediction frameworks using machine learning Bhende, Kabo Clifford; Sigwele, Tshiamo; Mokgethi, Chandapiwa; Maenge, Aone; Kuthadi, Venu Madhav
International Journal of Advances in Applied Sciences Vol 14, No 2: June 2025
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijaas.v14.i2.pp361-372

Abstract

Ischemic heart disease (IHD) is a leading cause of mortality worldwide, calling for advanced predictive models for timely intervention. Current literature reviews on machine learning (ML)-based IHD prediction frameworks often focus on predictive accuracy but lack depth in areas like dataset diversity, model interpretability, and privacy considerations. Existing IHD prediction frameworks face limitations, including reliance on small, homogenous datasets, limited critical analysis, and issues with model transparency, reducing their clinical utility. This review addresses these gaps through a systematic, comparative analysis of popular ML models, such as random forest (RF) and support vector machines (SVM), noting their strengths and limitations. Key contributions include a qualitative examination of prevalent tools, datasets, and evaluation metrics, identification of gaps in dataset diversity and interpretability; and recommendations for improving model transparency and data privacy. Major findings reveal a trend toward ensemble models for accuracy but highlight the need for explainable artificial intelligence (AI) to support clinical decisions. Future directions include using federated learning to enhance data privacy, integrating unstructured data for comprehensive prediction, and advancing explainable AI to build trust among healthcare providers. By addressing these areas, this review aims to guide future research toward developing robust, transparent ML frameworks that can be more effectively deployed in clinical settings.