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All Journal Muhammadiyah Journal of Geriatric Kieraha Medical Journal
Gunawan, Yusuf Adi
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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PROFIL UNDERLYING DISEASE PASIEN ACUTE KIDNEY INJURY KRITERIA RIFLE DI RUMAH SAKIT UMUM PKU MUHAMMADIYAH PURBALINGGA Athamevia, Nasywa; Gunawan, Yusuf Adi; Almanfaluthi, Muhammad Luthfi; Widodo, Oei Stefani Yuanita
Kieraha Medical Journal Vol 7, No 1 (2025): KIERAHA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran, Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/kmj.v7i1.9566

Abstract

Acute Kidney Injury (AKI) seringkali diartikan sebagai salah satu komplikasi dari sejumlah penyakit. Biasanya pasien akan memiliki suatu penyakit yang mendasari (underlying disease) sebelum terjadinya AKI, seperti anemia, diare, bahkan covid-19. Dari penelitian sebelumnya, belum terdapat informasi terkait apa saja underlying disease yang dapat menyebabkan AKI. Selain itu, juga belum ada penelitian yang mengkaji derajat AKI berdasarkan kriteria Risk, Injury, Failure, Loss, and End Stage Renal Disease (RIFLE) yang paling banyak terjadi. Tujuan dari penelitian ini adalah untuk mengetahui mayoritas penyakit yang mendasari dan derajat AKI yang paling banyak terjadi. Metode penelitian yang digunakan adalah observasional analitik dengan menggunakan rekam medis elektronik pasien AKI yang terdaftar dari Januari 2022 hingga Desember 2023. Terdapat sejumlah 107 sampel yang memenuhi kriteria inklusi dan eksklusi. Sample dikelompokkan berdasarkan kriteria data jenis kelamin, usia, hasil serum kreatinin, dan diagnosis dari awal pasien terdaftar. Komposisi kriteria jenis kelamin diperoleh hasil dengan persentase yang sama masing-masing 50%, selanjutnya komposisi usia terbanyak AKI sejumlah 57% berada pada usia tua dan sisanya 43% adalah usia muda. Hasil serum kreatinin pasien sebagian besar masih berada pada level Risk, serta terdapat beberapa underlying disease yang ditemukan pada pasien AKI yang kemudian digolongkan berdasarkan organnya. Underlying disease yang paling banyak dialami, antara lain anemia, gangguan pernapasan, dan gangguan pencernaan. Setiap underlying disease diperiksa kembali berdasarkan jenis kelamin, usia, dan serum kreatinin dengan kriteria RIFLE. Kesimpulannya, dari hasil yang didapatkan sesuai dengan penelianan.
The correlation between the neutrophil-to-lymphocyte ratio and the stage of acute kidney injury based on akin criteria in patients hospitalized Bustani, Bintang; Gunawan, Yusuf Adi; Karita, Dewi; Susiyadi, Susiyadi
Muhammadiyah Journal of Geriatric Vol. 5 No. 2 (2024): Muhammadiyah Journal of Geriatric
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mujg.5.2.61-67

Abstract

Background: Over the past few decades, the incidence of patients experiencing acute kidney injury (AKI) has increased, necessitating inpatient care. The prognosis of AKI patients is influenced by the management they receive, requiring swift and accurate intervention to prevent poor outcomes. Current AKI diagnostic biomarkers are considered slow, affecting the timeliness of treatment. This study aims to investigate the correlation between the neutrophil-to-lymphocyte ratio (NLR) and AKI as an early biomarker that has the potential to predict AKI. Objective: This study aims to determine whether there is a correlation between NLR and the stage of AKI using the AKIN criteria and the NLR cutoff for each stage of AKI. Methods: This study is a cross-sectional study. Subjects were selected using consecutive sampling. Data were collected using secondary data from the medical records of PKU Muhammadiyah Purbalingga Hospital. Results: We conducted 101 study subjects, there were 49 male and 52 female, with an average age of 62.3 years. Cardiovascular comorbidities were the most common among AKI patients, with 44 subjects affected. A significant correlation was found between NLR and the stage of AKI, as follows: a statistical analysis using ordinal logistic regression (p=0.044), odds ratio (1.03), and multivariate AUC test (77%), cut off (17.7) with specificity (71%) and sensitivity (75%). Conclusion: There is a correlation between NLR and the stage of AKI using AKIN criteria at PKU Muhammadiyah Purbalingga Hospital.
Co-Authors ALMANFALUTHI, MUHAMMAD LUTHFI Athamevia, Nasywa Bustani, Bintang Karita, Dewi Susiyadi, Susiyadi Widodo, Oei Stefani Yuanita