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All Journal Medicinus : Jurnal Kedokteran Sabda : Jurnal Teologi Kristen
Sirait, Endy Amos Todo Hasudungan
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Religion Humanities Education Medicine & Pharmacology Public Health Social Sciences Other

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Pola Hidup Sehat Berdasarkan 1 Korintus 6:19-20 untuk Pencegahan Human Metapneumovirus Sirait, Endy Amos Todo Hasudungan; Halomoan, Yan Kristian; Manurung, Chrismas Eben E; Jonathans, Kornelius Rulli
Sabda: Jurnal Teologi Kristen Vol 6, No 1 (2025): MEI
Publisher : Sekolah Tinggi Teologi Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55097/sabda.v6i1.252

Abstract

This study aims to explore the role of healthy lifestyle and spiritual approach in preventing human metapneumovirus (HMPV) infection, a respiratory virus that attacks at-risk groups such as children, the elderly, and individuals with weak immune systems. Using a literature study method and a descriptive qualitative approach, this study examines medical literature and spiritual principles from 1 Corinthians 6:19–20. The results of the study indicate that the implementation of a healthy lifestyle, including personal hygiene, balanced nutrition, adequate rest, and physical activity, plays an important role in strengthening the immune system and reducing the risk of HMPV infection. The integration of medical and spiritual approaches has been proven to provide a more holistic prevention strategy, not only reducing the risk of infection but also increasing collective awareness in society. This study recommends that health education be integrated with religious values to form a comprehensive and sustainable healthy lifestyle culture. Abstrak:Penelitian ini bertujuan untuk menggali peran pola hidup sehat dan pendekatan spiritual dalam pencegahan infeksi Human Metapneumovirus (HMPV), sebuah virus pernapasan yang menyerang kelompok yang beresiko seperti anak-anak, orang lanjut usia, dan individu dengan sistem imun yang lemah. Menggunakan metode studi pustaka dan pendekatan kualitatif deskriptif, penelitian ini menelaah literatur medis dan prinsip-prinsip spiritual dari 1 Korintus 6:19–20. Hasil kajian menunjukkan bahwa penerapan pola hidup sehat meliputi kebersihan pribadi, gizi seimbang, istirahat cukup, dan aktivitas fisik berperan penting dalam memperkuat sistem imun dan menurunkan risiko infeksi HMPV. Integrasi antara pendekatan medis dan spiritual teruji memberikan strategi pencegahan yang lebih holistik, tidak hanya mengurangi risiko infeksi tetapi juga meningkatkan kesadaran kolektif dalam masyarakat. Penelitian ini merekomendasikan agar edukasi kesehatan diintegrasikan dengan nilai-nilai keagamaan untuk membentuk budaya hidup sehat yang komprehensif dan berkelanjutan.Kata Kunci: HMPV, hidup sehat,penyakit , spiritualitas Kristen.
Evaluating the Effectiveness and Safety of a Shortened Rifapentine-Moxifloxacin Regimen in Treating Drug-Sensitive Pulmonary Tuberculosis: A Systematic Review Wicaksana, Luthfia Ayu; Sirait, Endy Amos Todo Hasudungan
Medicinus Vol. 15 No. 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i2.10976

Abstract

Background: Prolonged treatment duration remains a key challenge in managing drug-sensitive pulmonary tuberculosis (DS-TB), contributing to poor adherence and treatment failure. Recent evidence suggests that regimens incorporating rifapentine and moxifloxacin (RPT+MOX) may allow for effective 4-month treatment courses. Methods: We conducted a systematic review and meta-analysis following PRISMA 2020 guidelines to evaluate the effectiveness and safety of shortened RPT+MOX regimens. PubMed, EMBASE, and Scopus were searched up to May 2025. Eligible studies included randomized trials or observational cohorts comparing shortened RPT+MOX regimens with standard 6-month therapies in patients with DS-TB. Outcomes included culture conversion at 8 weeks, relapse or treatment failure, and serious adverse events. Risk of bias was assessed using the ROBINS-I tool. Result: Five studies (three RCTs, two observational) met inclusion criteria. Pooled analysis showed no significant difference in risk for relapse or treatment failure (RR 0.79, 95% CI: 0.37–1.67), culture conversion (RR 1.16, 95% CI: 0.80–1.69), or serious adverse events (RR 0.92, 95% CI: 0.65–1.29) between RPT+MOX and standard regimens. Risk of bias ranged from minimal to moderate. The GRADE assessment supported high certainty of evidence. Conclusions: Shortened RPT+MOX regimens demonstrate comparable effectiveness and safety to standard 6-month treatment for DS-TB, supporting their use in appropriate settings. Further studies are warranted to assess long-term outcomes, real-world adherence, and feasibility across diverse populations.
Co-Authors Halomoan, Yan Kristian Jonathans, Kornelius Rulli Manurung, Chrismas Eben E Wicaksana, Luthfia Ayu