Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Pediatric Sciences Journal Acta Neurologica Indonesia
Fadya, Vannisa
Unknown Affiliation
Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Epicutaneous immunotherapy for peanut allergy treatment in pediatrics: A literature review Fadya, Vannisa; Safira, Siti Sarah; Nabila, Amira Qisthy; Yufika, Amanda
Pediatric Sciences Journal Vol. 6 No. 1 (2025): Available online : 1 June 2025
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v6i1.109

Abstract

Peanut allergy in children is a growing public health concern that significantly affects patients' quality of life. Although oral immunotherapy (OIT) has shown effectiveness in desensitizing allergic reactions, it is associated with a threefold increased risk of anaphylaxis compared to strict avoidance. As an alternative, epicutaneous immunotherapy (EPIT) has emerged as a promising therapy due to its favorable safety profile, ease of administration, and non-invasive nature. However, despite increasing interest in EPIT, there is still limited evidence assessing its efficacy and safety in pediatric populations. This literature review aims to summarize current findings on the mechanism of desensitization, clinical efficacy, safety, and impact on quality of life associated with EPIT in managing peanut allergy in children. Relevant articles were identified through database searches in PubMed, Cochrane, Science Direct, Scopus, and Google Scholar using Medical Subject Headings (MeSH) and keyword combinations such as "Epicutaneous Immunotherapy", "Peanut Allergy", and "Pediatric Allergy". EPIT works by delivering peanut allergens through a patch applied to intact skin. The allergen is taken up by Langerhans cells and presented to the immune system, triggering regulatory T-cell (Treg) responses that reduce allergic sensitivity. Viaskin© is the most clinically advanced EPIT delivery system currently available. Findings from clinical studies indicate that EPIT is effective in inducing desensitization, with a lower risk of systemic reactions compared to OIT. Furthermore, EPIT contributes to improved quality of life in children with peanut allergy. These results support EPIT as a promising therapeutic option for pediatric peanut allergy management.
The Use of Robot-Assisted Gait Training (RAGT) to Improve Walking Independence in Stroke Rehabilitation: A Systematic Review Fadya, Vannisa; Amira Qisthy Nabila; Ardia Mirati Alsandi
Acta Neurologica Indonesia Vol. 3 No. 04 (2025): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v3i04.57

Abstract

Globally, stroke is the second leading cause of death and third in causing disability, although mortality rates have declined due to treatment advancements. This has led to an increased population of stroke survivors, with over 70% facing long-term motor, sensory, cognitive, or speech impairments, placing a substantial burden on families and society. Gait training plays a crucial role in enhancing daily living activities and independence. Currently, therapist-assisted rehabilitation is the primary approach, though it can be time-intensive and may lead to low adherence. However, technology is developing significantly in stroke rehabilitation with high-intensity, repetitive movements, potentially enhancing recovery. Therefore, current study aimed to conduct a systematic review of RCTs assessing the effectiveness of RAGT to improve walking independence. The outcome was the assessment of lower limb function using scales, such as the FAC, FMA-LE, and 6MWT. A thorough search was conducted in three databases. The risk for bias was evaluated using the Revised Tool RoB 2.0. There are inconsistent findings in the effectiveness of RAGT in improving motor function, walking ability, and walking endurance compared to conventional. But, RAGT showed promising results, particulary in the subacute phase. Peak neurologic recovery of stroke occurs within 1–3 months after the onset of stroke. From this time to 6 months, recovery slows down. In conclusion, the use of RAGT in stroke rehabilitation yielded a favorable and promising outcomes. However, the effectiveness compared to conventional therapy has not yet been consistently significant.
Co-Authors Amira Qisthy Nabila Ardia Mirati Alsandi Nabila, Amira Qisthy Safira, Siti Sarah Yufika, Amanda