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All Journal Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Intellektika: Jurnal Ilmiah Mahasiswa
Az Zahra, Maulidya Rachma
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Arts Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Nursing Public Health Social Sciences Veterinary

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Artikel Review: Formulasi dan Evaluasi Sediaan Tablet Lepas Lambat Az Zahra, Maulidya Rachma; Viola Putri Andini; Maharani Intan Rusita; Tiara Anisa Maharani; Eva Putri Wulandari; Farid Rahmandani; Aisyah Adellina Santyas; Dewi Rahmawati; Dzakiya Zhihrotulwirda; Yani Ambari; Fitrul Mubarak
An-Najat Vol. 3 No. 2 (2025): Mei : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i2.2719

Abstract

Zat aktif yang berbentuk padat bisa diberikan kepada pasien dalam bentuk serbuk, tetapi umumnya zat aktif diformulasikan menjadi sediaan padat yang disebut tablet. Tablet lepas lambat adalah jenis tablet yang dirancang untuk melepaskan zat aktif secara perlahan-lahan ke dalam tubuh selama waktu tertentu. Tujuan penelitian ini untuk mengetahui formulasi dan evaluasi yang terdapat  pada sediaan tablet lepas lambat. Metode yang diterapkan dalam review artikel ini adalah dengan mengumpulkan dan memilah dari beberapa jurnal dengan tema yang sesuai dan sama, kemudian kami review menjadi 7 jurnal yang tepat. Pemilihan jurnal didasarkan pada kriteria tertentu, seperti relevansi topik, kualitas publikasi, dan tahun terbit yang terbaru untuk memastikan keakuratan dan kekinian data. Hasil menunjukkan bahwa formulasi dan evaluasi memegang peranan penting dalam pengembangan tablet lepas lambat. Pemilihan eksipien (HPMC, xanthan gum, gelatin, pati alami modifikasi) dan metode formulasi (granulasi basah, kempa langsung, Simplex Lattice Design) mempengaruhi profil pelepasan obat, sifat fisik, dan stabilitas tablet. Kesimpulan: Pemilihan eksipien dan metode formulasi sangat penting dalam menentukan karakteristik tablet lepas lambat. Eksipien dan metode yang tepat dapat mengoptimalkan pelepasan zat aktif sesuai standar farmakope.  
Edukasi Pencegahan dan Penanganan Hipertensi pada Warga Dusun Plumpung Desa Galengdowo Az Zahra, Maulidya Rachma; Nungky Taniasari
Intellektika : Jurnal Ilmiah Mahasiswa Vol. 3 No. 5 (2025): Intellektika : Jurnal Ilmiah Mahasiswa
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/intellektika.v3i5.3379

Abstract

Hypertension is a growing health problem, especially among the elderly and low-educated communities. Hypertension continues to emerge as a critical public health challenge, with increasing incidence and uneven impact, particularly affecting the elderly population and low-educated communities. In response to this situation, a community-based study was conducted in Plumpung Hamlet, Galengdowo Village, with the main objective of increasing residents' knowledge and awareness of primary prevention strategies and self-management of hypertension. The intervention method applied was multimodal, including interactive health lectures, distribution of leaflets designed with easy-to-understand language and clear visuals, and provision of free blood pressure checks that served as a screening tool and immediate awareness. This research design used a participatory approach with pre-test and post-test instruments to measure quantitative changes in participants' understanding, accompanied by blood pressure monitoring activities to evaluate the impact of education on physical health indicators. The evaluation results showed the program's significant success, marked by a 57.69% increase in comprehension scores between the pre-test and post-test sessions, while also showing an improvement trend in the blood pressure values of most participants after completing the entire education series. These findings clearly affirm the fundamental role of sustainable and accessible health education as an effective community-based intervention to mitigate hypertension risk factors and ultimately improve holistic quality of life. The implications of this study highlight the urgency of implementing regular, structured, and targeted education programs, especially those targeting the most vulnerable demographic groups, as a long-term health investment to prevent morbidity and complications from hypertension.  
Co-Authors Aisyah Adellina Santyas DEWI RAHMAWATI Dzakiya Zhihrotulwirda Eva Putri Wulandari Farid Rahmandani Fitrul Mubarak Maharani Intan Rusita Nungky Taniasari Tiara Anisa Maharani Viola Putri Andini Yani Ambari