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All Journal Biofaal Journal Educatoria : Jurnal Ilmiah Ilmu Pendidikan
Setiawan, Maulana
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Biochemistry, Genetics & Molecular Biology Education Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences Other

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Peranan Karbohidrat dalam Perspektif Al-Qur’an Setiawan, Maulana; Wiratama, Ichsan; Sulaeman, Alif
Educatoria : Jurnal Ilmiah Ilmu Pendidikan Vol. 2 No. 4 (2022): October
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.66 KB) | DOI: 10.36312/ejiip.v2i4.131

Abstract

Carbohydrates are compounds consisting of the elements carbon, hydrogen and oxygen, carbohydrates have an important role for life for humans, animals and plants. Carbohydrates and their functions have been described in several verses of the Qur'an.. The perspective of the Qur'an on science, especially on carbohydrates, is sometimes less known to most people that carbohydrates are important to study. The abundance of food on this earth, makes humans less aware and negligent about the importance of the benefits of carbohydrates. The purpose of this study is to find out about the role of carbohydrates in the Qur'an, encourage the development of science in the perspective of the Qur'an, increase faith and gratitude for all God's gifts. The research method in this article uses literature studies, writing techniques to collect data and information by reviewing related journals and books. The result of writing this article is that carbohydrates have an important role, source and impact according to the view of the Qur'an. The conclusion obtained is that the role of carbohydrates has been explained in the Qur'an in the letter (Qur'an: 4, Al-Maidah: 88), the source of carbohydrates (Al-An'am: 95, Yasin: 33, Al-Baqarah: 22, An-nahl; 11, An-Nahl: 68-69), and its impact (Al-A'raf: 31, Al-Maidah: 87).
The Effectiveness of Stem Cell Therapy Compared to Conventional Therapy on Improving Pancreatic Beta Cell Function in Type 2 Diabetes Patients: A Systematic Review Setiawan, Maulana; Saraswati, Made Ratan; Darwinata, Agus Eka
Biofaal Journal Vol 7 No 1 (2026): Biofaal Journal (On Process)
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v7i1pp32-48

Abstract

More than 800 million people worldwide experience type 2 diabetes mellitus (T2DM), characterized by progressive pancreatic β-cell deterioration inadequately addressed by conventional treatments. This review assesses stem cell-based interventions versus standard therapy for β-cell functional restoration. Systematic review aims to comprehensively evaluate and compare the effectiveness of stem cell therapy versus conventional therapy in improving pancreatic β-cell function in type 2 diabetes patients. Systematic searches of PubMed, Cochrane Library, Web of Science, and Scopus from January 2015 to October 2025 retrieved 125 records. After duplicate removal and screening, 17 studies met the general inclusion criteria, of which six randomized controlled trials (RCTs) involving 339 participants were eligible for analysis. Primary outcomes were C-peptide concentrations, HOMA-β, HbA1c, insulin requirements, and safety parameters. The results showed that stem cell interventions consistently elevated fasting C-peptide levels to 1.9±1.0 ng/mL (versus 0.7±0.4 ng/mL in controls). Mean HbA1c reductions reached 0.67% (intervention 7.52±1.07% versus placebo 8.19±1.02%). Insulin dosage requirements decreased markedly, with reductions approaching 46.7%. Safety assessment remained limited due to incomplete adverse event documentation across included studies. Interpretation is further constrained by small trial sizes (23–91 participants) and protocol heterogeneity across cell sources, administration routes, and follow-up durations. Stem cell-based therapies demonstrate encouraging potential for enhancing pancreatic β-cell function in T2DM patients. Insufficient long-term follow-up data and inadequate safety surveillance preclude definitive clinical recommendations, supporting their application exclusively within structured clinical trial settings.
Co-Authors Agus Eka Darwinata Saraswati, Made Ratan Sulaeman, Alif Wiratama, Ichsan