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All Journal Jurnal Locus Penelitian dan Pengabdian Journal of Pharmaceutical and Sciences.
Ramatillah , Diana Laila
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Adherence to a Healthy Lifestyle Among Hypertensive Patients Based on Social Cognitive Theory in a Private Hospital in Bogor Wiraandini, Ni Putu Devi; Ramatillah , Diana Laila
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 7 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i7.4451

Abstract

Introduction: Hypertension management relies heavily on lifestyle modification, yet many patients remain non-adherent to healthy behaviours. This study aimed to assess the influence of sociodemographic, personal, and environmental factors on healthy lifestyle adherence among hypertensive patients, using the Social Cognitive Theory (SCT) framework. Methods: A cross-sectional study was conducted in July 2024 at a private hospital in Bogor, involving 239 hypertensive outpatients. Validated questionnaires assessed self-efficacy, self-regulation, social support, and adherence behaviours. Data were analyzed using Chi-square and Fisher’s Exact tests (p < 0.05). Results: Significant associations were found between age, BMI, number of children, and family history of hypertension with motivation, self-efficacy, self-regulation, social support, and lifestyle adherence. Age was significantly linked to motivation (p = 0.001), self-efficacy (p = 0.001), and self-regulation (p = 0.005). BMI correlated with illness perception (p = 0.002), self-regulation (p = 0.025), and adherence (p = 0.004). Number of children and family history of hypertension were also significantly related to multiple behavioural factors. Gender, education, and occupation showed no significant effects. Conclusion: Adherence to a healthy lifestyle among hypertensive patients is significantly influenced by age, BMI, number of children, and family history. SCT-based interventions should target personal and familial factors to improve lifestyle adherence and hypertension outcomes.
Evaluasi Penggunaan Eritropoetin (EPO) yang dikaitkan dengan Clinical Outcome pada Pasien Hemodialisis di RSUP Prof. R. D . Kandou Manado. Rambi, Firly Kartika Yuni; Ramatillah , Diana Laila
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.1043

Abstract

Background: Chronic kidney disease (CKD) is a health issue that occurs in almost all parts of the world, and the number of patients continues to increase. CKD patients undergoing hemodialysis often experience anemia, which affects their quality of life and increases the risk of morbidity and mortality. Erythropoietin (EPO) is used to treat anemia, but its effectiveness can be affected by nutritional status, combination therapy, and other factors. Objective: To determine the profile of EPO therapy in CKD patients at the Dahlia Hemodialysis Unit at RSUP Prof. Dr. R.D. Kandou. Methods: An observational study with a retrospective cohort design (January–December 2020 with follow-up until December 2024) and a prospective design (October–December 2024). Patient medical records were processed and analyzed descriptively and analytically using Independent T-Tests, ANOVA, ANCOVA, and Kaplan-Meier survival analysis. Results: 209 patients undergoing therapy, 109 male (52.15%) and 100 female (47.85%). The average increase in post-treatment hemoglobin levels (Hb Post) compared to pre-treatment levels (Hb Pre) was 16.28%. Independent T-Test showed no significant difference in Hb levels between males and females (p>0.05). ANOVA Test showed a significant difference in Hb Post levels between age groups (F(7,201)=3.517; p=0.001). ANCOVA analysis showed that Hb Pre was the primary predictor of Hb Post (F=161.151; p<0.001). Conclusion: EPO therapy increases hemoglobin levels in CKD patients, with the response influenced by age and Hb Pre, but not by gender. Hb Pre levels are the primary predictor of treatment success.
Co-Authors Rambi, Firly Kartika Yuni Wiraandini, Ni Putu Devi