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Modalitas Terbaru Pengobatan Luka Bakar Hafiz Khairun Marwan; Andi Irwansyah Achmad; Nurul Rumila Roem
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6184

Abstract

Burn injuries are complex tissue damage often accompanied by serious complications such as infection, systemic inflammation, and organ dysfunction. Effective burn management requires a comprehensive multidisciplinary approach, including infection control, local wound care, nutritional support, and regenerative therapy. Along with advances in science and technology, various novel treatment modalities have been developed to accelerate healing, reduce scarring, and improve patients’ quality of life. This study aims to evaluate the effectiveness and clinical prospects of the latest burn treatment modalities through a review of relevant literature from 2021 to 2025. This research employed a descriptive qualitative literature review method, analyzing 10 relevant scientific articles obtained from academic databases such as PubMed, ScienceDirect, and Google Scholar. The reviewed modalities include stem cell therapy, Platelet Rich Plasma (PRP), silver nanoparticles, nanofiber and hydrogel-based dressings, natural extracts such as aloe vera and binahong, as well as advanced technologies like smart dressings and low-level laser therapy. The results indicate that regenerative and smart technology-based approaches significantly enhance epithelialization, reduce infection, and improve tissue repair. Natural therapies also show promising potential as safe, affordable, and effective treatment alternatives. In conclusion, the integration of biological therapy, phytotherapy, and modern technology represents a promising direction in contemporary burn care. Further large-scale clinical research is needed to confirm the long-term safety and effectiveness of each modality.
The Role of Negative Pressure Wound Therapy in Burn Wound Healing Sitti Khusnul Khatima; Reeny Purnamasari; Nurul Rumila Roem; Agung Kurniawan; Dian Amelia Abdi
Jurnal EduHealth Vol. 17 No. 01 (2026): Jurnal EduHealt, January-March 2026
Publisher : Sean Institute

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Abstract

Burn injuries represent a major health concern with high morbidity and a substantial risk of complications, including infection, delayed wound healing, and skin graft failure. Negative Pressure Wound Therapy (NPWT) has emerged as an increasingly utilized therapeutic modality in burn management, working through mechanisms such as edema reduction, enhanced tissue perfusion, stimulation of granulation tissue formation, and effective exudate control. This study employed a Systematic Literature Review design conducted in accordance with the PRISMA guidelines. The findings indicate that NPWT provides significant positive effects on clinical outcomes, including accelerated wound healing, reduced infection rates, improved graft take following split-thickness skin graft procedures, and shorter hospital length of stay. Furthermore, NPWT has been shown to be effective in emergency department and intensive care unit settings as a bridging intervention prior to definitive surgical management in patients with severe burn injuries. Nevertheless, variability in study designs, negative pressure parameters, and application techniques remains a challenge for the standardization of therapeutic protocols. Therefore, further well-designed randomized controlled trials are required to optimize clinical guidelines and establish appropriate patient selection criteria. Overall, NPWT represents an effective and recommended therapeutic option in modern burn wound management.