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All Journal Al-Hayat: Natural Sciences, Health & Environment Journal
Eka Resi Kurniawan
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Agriculture, Biological Sciences & Forestry Earth & Planetary Sciences Education Environmental Science Health Professions Materials Science & Nanotechnology Public Health

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Variasi Genetik Gen LMP-1 HHV 4 berdasarkan Analisis RFLP Secara In silico: Genetic Variation of LMP-1 HHV 4 Gene based on In silico RFLP Analysis Rahma Windi Astuti; Khoirunnisa; Eka Resi Kurniawan
Al-Hayat: Natural Sciences, Health & Environment Journal Vol. 2 No. 2 (2024): Al-Hayat: Natural Sciences, Health & Environment Journal 
Publisher : Institut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/alhayat.v3i1.7927

Abstract

Human Herpesvirus 4 (HHV-4), also known as Epstein-Barr virus (EBV), is a member of the herpes virus family that has significant genetic variation. Molecular studies show that this variation can occur in genes that code for capsid proteins, DNA-binding proteins, and transcription-regulating proteins. In silico methods are used to determine mutations and genetic variations. The purpose of this study was to explore genetic variability in the LMP-1 HHV 4 gene sequence from NCBI PopSet 2581709082 using RFLP in silico. Restriction enzyme screening using restriction enzyme digest of DNA sites. RFLP in silico using the Benchling site. Genetic variability using the MEGA 11 application. The results obtained in silico screening of restriction enzymes and RFLP showed arelationship between PopSet 2581709082 genetic variation and HHV 4 LMP-1 genes, marked by the presence of five alleles, namely A1, A2, A3, A4, and A5.
Co-Authors KHOIRUNNISA Rahma Windi Astuti