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All Journal Jurnal Kesehatan Cendikia Jenius Multidisciplinary Indonesian Center Journal
Moh.Fairuz Abadi
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Religion Humanities Earth & Planetary Sciences Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary Other

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DIFFERENCES IN HEMATOCRIT LEVELS AND PLATELET COUNTS ON THE 4th To 6th DAY OF FEVER IN DENGUE HEMORRHAGIC FEVER PATIENTS Ni Luh Hepy Karniawan; Moh.Fairuz Abadi; A.A.Ayu Eka Cahyani
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 3 (2025): Vol. 2 No. 3 Edisi Juli 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i3.978

Abstract

Dengue Hemorrhagic Fever (DHF) is an endemic disease in Indonesia caused by the dengue virus and transmitted through the bites of Aedes aegypti and Aedes albopictus mosquitoes. The risk of serious complications primarily arises during the critical phase, typically between the 4th and 6th days of fever, during which plasma leakage may occur, leading to shock and severe bleeding. Hematocrit levels and platelet counts are important parameters in the diagnosis and monitoring of DHF patients. This study aimed to determine the differences in hematocrit levels and platelet counts during days 4 to 6 of fever in DHF patients at Prima Medika Hospital Denpasar, in February 2025. This research employed a descriptive quantitative design with purposive sampling, involving 35 patients who met the inclusion criteria. The results showed a decrease in hematocrit levels with averages of 42.8%, 42%, and 41.2%, and platelet counts with averages of 87 x 10³/µL, 59 x 10³/µL, and 47 x 10³/µL from day 4 to day 6 of fever. Data were analyzed using the Shapiro-Wilk normality test, the Friedman non-parametric test for hematocrit levels, and the Repeated Measures ANOVA parametric test for platelet counts. Statistical analysis showed a p-value of 0.002 for hematocrit levels and 0.000 for platelet counts. The conclusion of this study is that there are significant differences in hematocrit levels and platelet counts between days 4 to 6 of fever in DHF patients.
Overview of Germ Patterns and Sensitivity of Bacteria Causing Urinary Tract Infections in Westerindo Laboratory Nurrus Samsiah, Widiya; Didik Prasetya; Moh.Fairuz Abadi
Jurnal Kesehatan Cendikia Jenius Vol. 3 No. 1 (2025): Desember
Publisher : CV. CENDIKIA JENIUS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70920/jenius.v3i1.276

Abstract

Urinary tract infection (UTI) is a global health problem with high incidence and dynamic bacterial resistance patterns, requiring regular monitoring to ensure appropriate therapy. Irrational antibiotic use may worsen resistance. This study aimed to determine the bacterial patterns and antibiotic sensitivity of UTI pathogens at Westerindo Laboratory in 2023. A retrospective descriptive design with total sampling was applied to 137 patients who underwent urine culture from January to December 2023. Secondary data were obtained from the laboratory information system and analyzed using WHONET. Bacterial identification was performed through culture on Mac Conkey and blood agar, Gram staining, and Vitex 2 testing. Results showed that most respondents were female (55.47%). Of the 18 bacterial species identified, 83.3% were Gram-negative, with Escherichia coli as the predominant pathogen (30.65%), followed by Klebsiella pneumoniae (16.05%), Proteus mirabilis, and Morganella morganii (12.40%). Sensitivity testing of 327 antibiotics revealed 68.5% with high sensitivity, while Meropenem and Tigecycline showed 100% effectiveness against E. coli. Sixteen Extended Spectrum Beta Lactamase (ESBL) isolates were identified. In conclusion, UTIs were mainly caused by Gram-negative bacteria, particularly E. coli, with antibiotic resistance remaining a serious issue. Recommended Local antibiogram data, resistance monitoring, and antimicrobial stewardship are strongly recommended.
Co-Authors A.A.Ayu Eka Cahyani Didik Prasetya Ni Luh Hepy Karniawan Nurrus Samsiah, Widiya