Novita Trianah
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Tinjauan Ilmiah terhadap Sel Punca Dewasa: Peran Terapeutik, Keamanan, dan Aplikasinya dalam Penyakit Degeneratif Novita Trianah; Saptiawati Saptiawati; Ceni Liswati; Rina Hidayati Pratiwi
Jurnal Cakrawala Pendidikan dan Biologi Vol. 2 No. 3 (2025): September: Jurnal Cakrawala Pendidikan dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jucapenbi.v2i3.565

Abstract

Stem cells are unspecialized cells with the ability to self-renew over long periods of time without undergoing significant changes in their basic properties. The discovery of adult stem cells has revolutionized therapeutic and regenerative medicine and led to the development of new therapies for previously untreatable terminal conditions. Hematopoietic stem cell transplantation was the first example of successful stem cell therapy and has been widely used in the treatment of a variety of diseases, including leukemia, adult T-cell lymphoma, and multiple myeloma. Meanwhile, autologous mesenchymal stem cell transplantation is increasingly being used to repair mesenchymal tissues and other organs such as the lung and heart, and has shown promise in the treatment of stroke, multiple sclerosis, and diabetes. Interest in the therapeutic potential of other adult stem cells including neural, mammary, intestinal, inner ear, and testicular stem cells is also growing. The discovery of induced pluripotent stem cells has opened new insights into the epigenetic mechanisms underlying pluripotency and carcinogenesis. This study employed a qualitative approach with a literature review method, aiming to conduct an in-depth review of the scientific literature related to the development of stem cell therapy and its epigenetic implications. Through a systematic analysis of various academic sources, this study seeks to formulate a comprehensive conceptual understanding and identify future directions for safer and more targeted stem cell therapy development.
Strategi Implementasi Manajemen Pendidikan Inklusif di Sekolah Menengah: Studi Kasus di SMP Negeri 4 Babelan Julinda Siregar; Novita Trianah; Ceni Liswati; Saptiawati Saptiawati
Jurnal Nakula : Pusat Ilmu Pendidikan, Bahasa dan Ilmu Sosial Vol. 3 No. 6 (2025): Jurnal Nakula : Pusat Ilmu Pendidikan, Bahasa dan Ilmu Sosial
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/nakula.v3i6.2292

Abstract

This study aims to describe and analyze the implementation of inclusive education management at SMP Negeri 4 Babelan. Inclusive education is an educational approach that provides learning opportunities for all students without discrimination, including those with special educational needs (ABK). This concept emphasizes the importance of a friendly, adaptive, and responsive learning environment to student diversity. This study uses a qualitative descriptive approach with data collection techniques through in-depth interviews, participatory observation, and documentation studies. Informants in this study consisted of the principal, regular teachers, special assistant teachers, students with special needs, and their parents. The results of the study indicate that inclusive education management at SMP Negeri 4 Babelan has been implemented through four main management functions, namely: (1) strategic planning integrated into the annual school work program, including budget allocation for inclusion needs; (2) organizing an inclusion team involving teachers, education staff, and the school committee; (3) implementing adaptive learning based on a differentiation and individualization approach, adjusted to students' abilities and learning styles; and (4) evaluations conducted periodically to assess students' academic and social-emotional development, as well as the effectiveness of the inclusion program as a whole. However, this study also identified several obstacles, including a limited number of special assistant teachers, a lack of professional training for regular teachers, and a lack of supporting facilities such as therapy rooms or learning aids. Furthermore, factors supporting the program's success include the school leadership's commitment to mainstreaming inclusion, a collaborative spirit among teachers, and the support and active involvement of parents. Based on these findings, this study recommends several strategic steps, such as strengthening teacher training in inclusive classroom management and adding special assistant teachers as needed.