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ISCEMIC STROKE IN PREGNANT WOMEN WITH AUTOIMMUNE HEMOLYTIC ANEMIA (AIHA) AND ANTIPHOSPHOLIPID SYNDROME (APS) Fakhrurrazy, Fakhrurazy; Khatimah, Husnul
MNJ (Malang Neurology Journal) Vol. 11 No. 2 (2025): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.02.14

Abstract

Background: An increased risk of thrombosis has been described in patients with autoimmune hemolytic anemia (AIHA) and antiphospholipid syndrome (APS), including stroke. The clinical manifestations of AIHA and APS occur due to thrombosis and embolism that spread to large and small blood vessels which can cause ischemia and infarction in tissues, including the blood vessels of the brain. Objective: There is a hypothesis states that free hemoglobin in AIHA and APS will cause endothelial dysfunction, inflammation, and procoagulant state that can increase the risk of stroke. This study aims to know what may caused ischemic stroke in pregnant women with autoimmune hemolytic anemia (AIHA) and antiphospholipid syndrome (APS). Methods: This is a case report of AIHA in a pregnant woman with ischemic stroke accompanied by a literature review. Conclusion: This case represents a rare arterial ischemic complication of AIHA and APS that may be associated with hypercoagulable state. Approximately 15-20% of AIHA cases are associated with arterial or venous thrombosis, and recent studies have shown an increased risk of ischemic stroke among patients with primary AIHA, especially in the first year after diagnosis.
EDUKASI DAN SKRINING DEMENSIA DI MASJID AL JIHAD BANJARMASIN DALAM UPAYA PENCEGAHAN DEMENSIA PADA LANSIA Fakhrurrazy, Fakhrurazy; Runtuwene, lily; Pambudi, Pagan; Steven, Steven; Dafif, Muhammad Welly; Handayani, Fitriah; Khatimah, Husnul
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 8 (2025): Penguatan Ekonomi Masyarakat Berbasis Ekologis untuk Mencapai Keberlanjutan Menuju Ind
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37695/pkmcsr.v8i0.2777

Abstract

Dementia is a brain disorder that causes a decline in memory, thinking ability, and behavior, which significantly affects the quality of life of older adults. According to data from the World Health Organization (WHO, 2023), more than 55 million people worldwide live with dementia, and this number continues to increase, particularly in low- and middle-income countries such as Indonesia. The low level of public awareness regarding the early symptoms of dementia has led to many undetected cases. This community service activity aimed to provide education about dementia to the congregation of Al Jihad Mosque in Banjarmasin and to conduct cognitive function screening using the Mini-Mental State Examination (MMSE) as an early detection effort. The activity was carried out on September 20, 2025, at Al Jihad Mosque, Banjarmasin, through educational sessions and dementia screening performed by a neurologist. A total of 49 participants took part in the activity, the majority aged 60–74 years (63.2%). The results showed that 97.9% of participants had normal cognitive function, while 2.0% exhibited a tendency toward cognitive impairment. These findings indicate the importance of routine screening among the elderly population, even when general cognitive function appears normal. This activity demonstrates that a faith-based community approach is effective in increasing awareness and promoting dementia prevention at the community level. Keywords: