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All Journal Jurnal Kedokteran Brawijaya Asian Journal of Health Research
Fadli, M Luqman
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Asherman's Syndrome due to Endometrial Tuberculosis: A Case Report and Literature Review Pratama, Anugerah Justi; Prabowo, Adityo; Tantular, Rezki; Fadli, M Luqman
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.251

Abstract

Introduction: Female genital tuberculosis, a rare form of extrapulmonary TB, often goes underdiagnosed despite its potential to cause significant reproductive complications such as amenorrhea and infertility. The theory behind this case emphasizes the need for heightened awareness and improved diagnostic approaches to effectively manage endometrial TB and its associated intrauterine adhesions. Case Presentation: A 31-year-old woman presented with a four-year history of oligomenorrhea and 3.5 years of primary infertility, undergoing various treatments including hormone therapy and ultrasound evaluations that revealed intrauterine masses and cervical issues. Following a hysteroscopic surgery that identified cervical stenosis and a tuberculous mass, she was treated for endometrial tuberculosis with anti-tuberculosis medication. Despite treatment, she continued to experience abnormal menstrual cycles, leading to further hysteroscopic evaluations that indicated significant uterine fibrosis and chronic cervicitis. The patient declined the insertion of a levonorgestrel-releasing intrauterine system (LNG-IUS) but received a Depo Medroxy Progesterone Acetate (DMPA) injection and was fitted with an IUD, alongside hormonal therapy with cycloproginova, with ongoing assessments showing improvements in uterine vascularity and visibility of the fallopian tubes. Conclusion: This case highlights the complexities of managing secondary amenorrhoea due to genital tuberculosis, which disrupts endometrial function and results in significant intrauterine adhesions. A multidisciplinary approach, involving hysteroscopic adhesiolysis, anti-tubercular therapy, and postoperative hormonal interventions, is crucial for effective treatment. Despite the restoration of menstrual cycles, ongoing fertility risks and pregnancy complications necessitate thorough preconception counselling and long-term monitoring.
A Case of  HIV and Disseminated Tuberculosis: Unrecognized Co-Infection and the Importance of Early Diagnosis Rosandy, Milanitalia Gadys; Fadli, M Luqman; Nurdiana, Farah; Kamal Hadi, Muchamad
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.9

Abstract

Tuberculosis (TB) is still the main cause of death in people living with HIV (PLHIV). TB preventive therapy (TPT) and ARVs can reduce morbidity, mortality, and incidence of TB in PLHIV. With the severity of the immunodeficiency, extrapulmonary TB or disseminated TB occurs more often. Disseminated TB occurs due to the hematogenous spread of Mycobacterium tuberculosis, which occurs as a result of progressive primary infection or reactivation of latent TB infection. Disseminated TB can involve many organs such as the lungs, liver, and spleen. Delays in diagnosis often occur due to non-specific clinical manifestations; thus, the diagnosis needs to be supported by radiological and microbiological examination, as well as definite histopathological diagnosis. Treatment is given according to existing therapy guidelines with a more extensive duration and regard to the patient's clinical condition.
Co-Authors Kamal Hadi, Muchamad Nurdiana, Farah Prabowo, Adityo Pratama, Anugerah Justi Rosandy, Milanitalia Gadys Tantular, Rezki