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All Journal Best Journal (Biology Education, Sains and Technology) Deli Medical and Health Science Journal
Ginting, Hana Isal Salina
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Nursing Public Health Other

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Hubungan IgG Dan IgM Dengue Terhadap Jumlah Trombosit Pada Pasien Demam Berdarah Dengue Di Rumah Sakit Umum Daerah Kota Padangsidempuan Sulastri, Sulastri; Ginting, Hana Isal Salina; Sembiring, Sella Elita; Harahap, Mery Silvia; Girsang, Rostiodertina; Tarigan, Ratna Sari Putri
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 2 (2024): September 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i2.11953

Abstract

Demam berdarah dengue (DBD) adalah penyakit menular yang ditransmisikan oleh nyamuk Aedes aegypti dan Aedes albopictus yang hidup di negara-negara tropis dan subtropis. Penelitian ini bertujuan untuk untuk mengetahui hubungan hasil pemeriksaan IgG/IgM dengue terhadap hasil trombosit pada pasien demam berdarah di Rumah Sakit Umum Daerah Padangsidimpuan. Desain penelitian observasional anaitik dengan menggunakan pendekatan cross sectional. Populasi adalah pasien demam berdarah dengue di RSUD Padangsidimpuan yang melakukan pemeriksanaan IgG dan IgM serta pemeriksaan jumlah trombosit sebanyak 18 orang. Dari 18 responden terdapat 14 responden (78%) IgG dan IgM dengue kategori negatif (-) terhadap jumlah trombosit pasien demam berdarah kategori rendah, sementara 4 responden (22%) IgG dan IgM dengue kategori positif (+) terhadap jumlah trombosit pasien demam berdarah kategori normal. Hasil analisis diketahui bahwa nilai probabilitasnya (0,02)
HUBUNGAN UMUR DAN FAKTOR PREDISPOSISI DENGAN INFEKSI SALURAN KEMIH PADA PASIEN RAWAT INAP DI RSUP H. ADAM MALIK MEDAN Ginting, Hana Isal Salina
Deli Medical and Health Science Journal Vol 2 No 2 (2025): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v2i2.2322

Abstract

Urinary tract infections (UTIs) are often found in hospitalized patients, with several health conditions potentially playing a role. This study explores whether factors like age, diabetes (DM), HIV, kidney issues, and autoimmune diseases are linked to UTIs in patients at RSUP H. Adam Malik Medan. Methods, Using a cross-sectional design, data were gathered from 59 UTI patients in the hospital. Researchers reviewed their age and health status—including DM, HIV, kidney disease, and autoimmune conditions—and used Chi-Square and Fisher’s Exact tests to check for any associations. Results, No significant connections were identified between UTIs and any of the examined factors, including age (p=0.869), DM, HIV, kidney disease, or autoimmune disorders. The presence or absence of these conditions did not notably affect UTI occurrence. Conclusion, This study found that common risk factors like age and certain chronic diseases do not significantly impact UTI rates among patients in this hospital. These insights can help guide future UTI prevention efforts in clinical settings.
HUBUNGAN PENINGKATAN ANTIBODY Ig A ANTI EA EBV PADA PASIEN PENDERITA KNF PADA SUKU NIAS Ginting, Hana Isal Salina
Deli Medical and Health Science Journal Vol 3 No 1 (2025): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v3i1.2741

Abstract

Nasopharyngeal carcinoma (NPC) is a malignant tumor of the head and neck region, predominantly found in Southeast Asia, and is closely associated with Epstein–Barr Virus (EBV) infection. Detection of Immunoglobulin A (IgA) antibodies against the Early Antigen (EA) of EBV has been recognized as a potential non-invasive biomarker for early diagnosis. Genetic, environmental, and lifestyle factors — including the traditional habit of consuming preserved foods among the Nias ethnic group — are believed to influence the antibody response. This study aimed to analyze the association between elevated IgA anti-EA EBV antibody levels and the occurrence of NPC among Nias patients. An observational analytic study with a case–control design was conducted involving 29 NPC patients and 29 healthy Nias individuals as controls. Serum samples were examined serologically at the Integrated Laboratory, Faculty of Medicine, University of North Sumatra. Data were analyzed using the Chi-square and Mann–Whitney tests. The findings revealed that the mean level of IgA anti-EA EBV antibodies in NPC patients (246.22 ± 320.05 U/mL) was significantly higher than that of healthy controls (51.79 ± 1.55 U/mL) (p < 0.05). Positive serological reactivity was detected in 55.2% of NPC patients compared to 10.3% in the control group. No significant associations were found between age or gender and the serological results (p > 0.05). These results indicate that elevated IgA anti-EA EBV antibody levels may serve as an important immunological marker for early detection of NPC, particularly among high-risk populations such as the Nias ethnic group.
Co-Authors Girsang, Rostiodertina Harahap, Mery Silvia Sembiring, Sella Elita Sulastri Sulastri Tarigan, Ratna Sari Putri