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All Journal Majalah Kedokteran Gigi Indonesia
Estuningtyas, Maria Felicitas Ajeng
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Dentistry

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Exploring the potential of bromelain in orthodontic treatment Estuningtyas, Maria Felicitas Ajeng; Karunia, Dyah; Retnaningrum, Yanuarti
Majalah Kedokteran Gigi Indonesia Vol 11, No 2 (2025): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.109296

Abstract

Bromelain, a proteolytic enzyme derived from pineapple, has attracted significant attention in both medicine and dentistry due to its diverse therapeutic properties. It has been widely studied for its anti-inflammatory, digestive, and wound-healing effects. In dentistry, bromelain has been investigated for applications such as reducing postoperative pain, facilitating enamel deproteinization, aiding in caries removal, and serving as an endodontic irrigant. In orthodontics, its potential lies in deproteinizing enamel to improve the bond strength of orthodontic brackets during placement. Studies suggest that applying bromelain prior to acid etching can enhance bracket bond strength, providing a safer and more efficient alternative to sodium hypochlorite. It has also shown promise in reducing plaque accumulation and gingivitis, particularly in patients with fixed orthodontic appliances. Bromelain’s antibacterial and anti-inflammatory properties support its role in maintaining oral hygiene and promoting healing. However, most existing evidence comes from in vitro or short-term clinical studies. Long-term clinical trials are needed to confirm its safety and efficacy in routine orthodontic practice.
Co-Authors Dyah Karunia Retnaningrum, Yanuarti