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ANTI-INFLAMMATORY ACTIVITY OF CILACAP-ORIGINAL Virgin Coconut Oil (VCO) USING THE PROTEIN DENATURATION METHOD Utami, Tri Fitri Yana; Asep Nurrahman; Fatikah
SAINS INDONESIANA Vol. 3 No. 4 (2025): Vol. 3, No. 4 Edisi Agustus 2025
Publisher : Gamma Publishing

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Abstract

Inflammation is the body's attempt to deactivate or destroy invading organisms, eliminate irritation, and prepare the stage for tissue repair. Many anti-inflammatory agents can be used, one of which is Virgin Coconut Oil (VCO). This study aims to determine the anti-inflammatory potential of original Cilacap VCO using the protein denaturation method. Furthermore, absorbance measurements were carried out using UV-Vis Spectrophotometry. The anti-inflammatory potential of VCO using the protein denaturation method has an IC50 of 14.05 ppm, which is categorized as very strong because it has a range of <50. This proves that VCO has the potential as an anti-inflammatory.